Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_2098PFAM: TrkA-N domain protein; sodium/hydrogen exchanger; KEGG: plt:Plut_0668 glutathione-regulated potassium-efflux system protein KefC, putative; Belongs to the monovalent cation:proton antiporter 2 (CPA2) transporter (TC 2.A.37) family. (584 aa)    
Predicted Functional Partners:
Ppha_2097
PFAM: alpha/beta hydrolase fold; KEGG: cph:Cpha266_0919 alpha/beta hydrolase fold.
 
     0.598
Ppha_2371
KEGG: gur:Gura_1460 hypothetical protein.
 
   
 0.531
Ppha_2099
Hypothetical protein.
       0.529
Ppha_2100
PFAM: RNP-1 like RNA-binding protein; KEGG: cch:Cag_1551 RNA-binding region RNP-1 (RNA recognition motif).
       0.525
Ppha_2703
KEGG: cph:Cpha266_2542 aspartate kinase; TIGRFAM: aspartate kinase; PFAM: aspartate/glutamate/uridylate kinase; homoserine dehydrogenase; amino acid-binding ACT domain protein; homoserine dehydrogenase NAD-binding.
     
 0.477
ribBA
3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family.
   
 
 0.464
msrA
Peptide methionine sulfoxide reductase; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
     
 0.464
Ppha_1543
TIGRFAM: ATPase, P-type (transporting), HAD superfamily, subfamily IC; PFAM: cation transporting ATPase domain protein; Haloacid dehalogenase domain protein hydrolase; E1-E2 ATPase-associated domain protein; KEGG: cph:Cpha266_0173 ATPase, P-type (transporting), HAD superfamily, subfamily IC.
 
 
 0.460
Ppha_2101
KEGG: cch:Cag_1552 hypothetical protein.
       0.442
Ppha_0781
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: plt:Plut_0502 glutamate synthase (ferredoxin).
  
  
 0.438
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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