STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
Ppha_2155PFAM: heat shock protein Hsp20; KEGG: cch:Cag_1892 heat shock protein, HSP20 family; Belongs to the small heat shock protein (HSP20) family. (132 aa)    
Predicted Functional Partners:
Ppha_0774
PFAM: heat shock protein Hsp20; KEGG: pvi:Cvib_0315 heat shock protein HSP20; Belongs to the small heat shock protein (HSP20) family.
  
  
 
0.906
Ppha_1812
KEGG: plt:Plut_0695 hypothetical protein; Belongs to the small heat shock protein (HSP20) family.
     
  0.900
dnaK
Chaperone protein DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.751
Ppha_0245
PFAM: AAA ATPase central domain protein; Clp domain protein; SMART: AAA ATPase; KEGG: cph:Cpha266_2449 AAA ATPase, central domain protein; Belongs to the ClpA/ClpB family.
  
 
 0.613
Ppha_2617
PFAM: UvrB/UvrC protein; AAA ATPase central domain protein; Clp domain protein; ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cph:Cpha266_0334 ATPase AAA-2 domain protein; Belongs to the ClpA/ClpB family.
  
 
 0.613
Ppha_2812
ATPase AAA-2 domain protein; PFAM: ATPase associated with various cellular activities AAA_5; ATPase AAA-2 domain protein; SMART: AAA ATPase; KEGG: cph:Cpha266_2577 ATPase AAA-2 domain protein.
  
 
 0.613
Ppha_1232
KEGG: cph:Cpha266_2261 DnaK like protein; Belongs to the heat shock protein 70 family.
  
 
 0.473
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
 
 0.442
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 
 0.433
Ppha_2154
PFAM: regulatory protein ArsR; KEGG: plt:Plut_0623 putative transcriptional regulator, ArsR family.
       0.426
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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