STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cas2-2CRISPR-associated protein Cas2; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Functions as a ssRNA-specific endoribonuclease. Involved in the integration of spacer DNA into the CRISPR cassette. (94 aa)    
Predicted Functional Partners:
cas1-2
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.995
cas1
CRISPR-associated protein Cas1; CRISPR (clustered regularly interspaced short palindromic repeat), is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain spacers, sequences complementary to antecedent mobile elements, and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Acts as a dsDNA endonuclease. Involved in the integration of spacer DNA into the CRISPR cassette.
 
 
 0.952
Ppha_1661
CRISPR-associated protein Cas4; CRISPR (clustered regularly interspaced short palindromic repeat) is an adaptive immune system that provides protection against mobile genetic elements (viruses, transposable elements and conjugative plasmids). CRISPR clusters contain sequences complementary to antecedent mobile elements and target invading nucleic acids. CRISPR clusters are transcribed and processed into CRISPR RNA (crRNA). Belongs to the CRISPR-associated exonuclease Cas4 family.
 
 
 
 0.936
Ppha_2457
KEGG: cph:Cpha266_2052 hypothetical protein.
 
     0.749
Ppha_2456
KEGG: mmw:Mmwyl1_2687 hypothetical protein.
       0.658
Ppha_1657
TIGRFAM: CRISPR-associated helicase Cas3; SMART: DEAD-like helicases; KEGG: dvl:Dvul_2978 metal dependent phosphohydrolase.
 
  
 0.653
Ppha_1658
TIGRFAM: CRISPR-associated protein Cas5 family; CRISPR-associated protein Cas5; KEGG: dvl:Dvul_2977 CRISPR-associated protein Cas5 family.
 
   
 0.616
Ppha_1660
TIGRFAM: CRISPR-associated protein, CT1132 family; CRISPR-associated protein, Csd2 family; PFAM: CRISPR-associated protein TM1801; KEGG: cph:Cpha266_1433 CRISPR-associated protein, Csd2 family.
 
   
 0.604
Ppha_1659
TIGRFAM: CRISPR-associated protein, Csd1 family; PFAM: CRISPR-associated protein CT1133; KEGG: drm:Dred_1004 CRISPR-associated protein, Csd1 family.
 
   
 0.473
Ppha_2454
TIGRFAM: CRISPR-associated protein, Csm1 family; KEGG: cph:Cpha266_2050 CRISPR-associated protein, Csm1 family.
 
   
 0.434
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.