Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_2496KEGG: cph:Cpha266_2166 hydrogenase/sulfur reductase, beta subunit. (359 aa)    
Predicted Functional Partners:
Ppha_2497
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; Oxidoreductase FAD-binding domain protein; KEGG: cch:Cag_1567 hydrogenase/sulfur reductase, gamma subunit.
  
 0.978
Ppha_2498
PFAM: NADH ubiquinone oxidoreductase 20 kDa subunit; KEGG: cph:Cpha266_2168 NADH ubiquinone oxidoreductase, 20 kDa subunit.
 
   
 0.952
Ppha_2499
PFAM: nickel-dependent hydrogenase large subunit; KEGG: cph:Cpha266_2169 nickel-dependent hydrogenase, large subunit.
 
   
 0.950
Ppha_1302
PFAM: oxidoreductase FAD/NAD(P)-binding domain protein; KEGG: cph:Cpha266_1256 oxidoreductase FAD/NAD(P)-binding domain protein.
  
 0.910
Ppha_1304
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_1258 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
 
     0.675
Ppha_1307
CoB--CoM heterodisulfide reductase; PFAM: protein of unknown function DUF224 cysteine-rich region domain protein; KEGG: cch:Cag_1028 heterodisulfide reductase, subunit C/succinate dehydrogenase, subunit C.
 
 
 
 0.664
Ppha_2495
PFAM: peptidase U32; KEGG: cph:Cpha266_2165 peptidase U32.
       0.571
Ppha_1306
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; KEGG: cph:Cpha266_1260 4Fe-4S ferredoxin, iron-sulfur binding domain protein.
 
   
 0.527
Ppha_1305
PFAM: methyl-viologen-reducing hydrogenase delta subunit; KEGG: cph:Cpha266_1259 methyl-viologen-reducing hydrogenase, delta subunit.
 
   
 0.505
Ppha_0695
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; KEGG: cph:Cpha266_0571 pyruvate flavodoxin/ferredoxin oxidoreductase domain protein.
     
 0.461
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
Server load: low (18%) [HD]