Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_2546PFAM: ABC transporter related; SMART: AAA ATPase; KEGG: pvi:Cvib_0353 ABC transporter related. (244 aa)    
Predicted Functional Partners:
Ppha_2369
PFAM: permease YjgP/YjgQ family protein; KEGG: cch:Cag_0302 hypothetical protein.
 
 
 0.986
Ppha_1901
PFAM: permease YjgP/YjgQ family protein; KEGG: pvi:Cvib_1109 permease YjgP/YjgQ family protein.
 
 
 0.982
Ppha_0409
PFAM: protein of unknown function DUF1239; KEGG: cph:Cpha266_0380 hypothetical protein.
  
 
 0.950
Ppha_2797
KEGG: cph:Cpha266_2554 hypothetical protein.
  
  
 0.832
lpxA
acyl-(acyl-carrier-protein)--UDP-N- acetylglucosamine O-acyltransferase; Involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
  
 0.789
lpxD
UDP-3-O-(3-hydroxymyristoyl) glucosamine N-acyltransferase; Catalyzes the N-acylation of UDP-3-O-acylglucosamine using 3- hydroxyacyl-ACP as the acyl donor. Is involved in the biosynthesis of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell. Belongs to the transferase hexapeptide repeat family. LpxD subfamily.
 
  
 0.719
Ppha_0432
TIGRFAM: outer membrane protein assembly complex, YaeT protein; PFAM: surface antigen (D15); surface antigen variable number repeat protein; Polypeptide-transport-associated domain protein ShlB-type; KEGG: cph:Cpha266_0397 surface antigen (D15).
 
  
 0.692
Ppha_0436
KpsF/GutQ family protein; KEGG: cch:Cag_0467 KpsF/GutQ; TIGRFAM: KpsF/GutQ family protein; PFAM: CBS domain containing protein; sugar isomerase (SIS); Belongs to the SIS family. GutQ/KpsF subfamily.
 
  
 0.665
Ppha_0443
lipid-A-disaccharide synthase; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
 
   
 0.652
Ppha_2547
SMART: metal-dependent phosphohydrolase HD region; KEGG: cph:Cpha266_2274 metal dependent phosphohydrolase.
       0.651
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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