node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ppha_0928 | Ppha_1031 | Ppha_0928 | Ppha_1031 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 0.717 |
Ppha_0928 | Ppha_1890 | Ppha_0928 | Ppha_1890 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.751 |
Ppha_0928 | guaB | Ppha_0928 | Ppha_1790 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.429 |
Ppha_0928 | ribBA | Ppha_0928 | Ppha_0726 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.768 |
Ppha_0928 | ribH | Ppha_0928 | Ppha_2709 | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.754 |
Ppha_1031 | Ppha_0928 | Ppha_1031 | Ppha_0928 | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.717 |
Ppha_1031 | ribH | Ppha_1031 | Ppha_2709 | Ribosomal protein L21; This protein binds to 23S rRNA in the presence of protein L20; Belongs to the bacterial ribosomal protein bL21 family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.700 |
Ppha_1886 | Ppha_1890 | Ppha_1886 | Ppha_1890 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: cph:Cpha266_0952 riboflavin synthase subunit alpha. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.999 |
Ppha_1886 | ribBA | Ppha_1886 | Ppha_0726 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: cph:Cpha266_0952 riboflavin synthase subunit alpha. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
Ppha_1886 | ribH | Ppha_1886 | Ppha_2709 | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: cph:Cpha266_0952 riboflavin synthase subunit alpha. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.998 |
Ppha_1890 | Ppha_0928 | Ppha_1890 | Ppha_0928 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.751 |
Ppha_1890 | Ppha_1886 | Ppha_1890 | Ppha_1886 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | TIGRFAM: riboflavin synthase, alpha subunit; PFAM: Lumazine-binding protein; KEGG: cph:Cpha266_0952 riboflavin synthase subunit alpha. | 0.999 |
Ppha_1890 | guaB | Ppha_1890 | Ppha_1790 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.525 |
Ppha_1890 | metK | Ppha_1890 | Ppha_2094 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | Methionine adenosyltransferase; Catalyzes the formation of S-adenosylmethionine (AdoMet) from methionine and ATP. The overall synthetic reaction is composed of two sequential steps, AdoMet formation and the subsequent tripolyphosphate hydrolysis which occurs prior to release of AdoMet from the enzyme. | 0.535 |
Ppha_1890 | ribBA | Ppha_1890 | Ppha_0726 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 3,4-dihydroxy-2-butanone 4-phosphate synthase; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the N-terminal section; belongs to the DHBP synthase family. | 0.999 |
Ppha_1890 | ribH | Ppha_1890 | Ppha_2709 | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.992 |
gmhA | ribH | Ppha_2710 | Ppha_2709 | Phosphoheptose isomerase; Catalyzes the isomerization of sedoheptulose 7-phosphate in D-glycero-D-manno-heptose 7-phosphate; Belongs to the SIS family. GmhA subfamily. | 6,7-dimethyl-8-ribityllumazine synthase; Catalyzes the formation of 6,7-dimethyl-8-ribityllumazine by condensation of 5-amino-6-(D-ribitylamino)uracil with 3,4-dihydroxy-2- butanone 4-phosphate. This is the penultimate step in the biosynthesis of riboflavin. | 0.752 |
guaB | Ppha_0928 | Ppha_1790 | Ppha_0928 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Sun protein; Specifically methylates the cytosine at position 967 (m5C967) of 16S rRNA. | 0.429 |
guaB | Ppha_1890 | Ppha_1790 | Ppha_1890 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | Riboflavin biosynthesis protein RibD; Converts 2,5-diamino-6-(ribosylamino)-4(3h)-pyrimidinone 5'- phosphate into 5-amino-6-(ribosylamino)-2,4(1h,3h)-pyrimidinedione 5'- phosphate; In the C-terminal section; belongs to the HTP reductase family. | 0.525 |
guaB | pyrB | Ppha_1790 | Ppha_2055 | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | KEGG: cch:Cag_1334 aspartate carbamoyltransferase catalytic subunit; TIGRFAM: aspartate carbamoyltransferase; PFAM: aspartate/ornithine carbamoyltransferase Asp/Orn-binding region; aspartate/ornithine carbamoyltransferase carbamoyl-P binding domain; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family. | 0.485 |