node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Ppha_2579 | Ppha_2837 | Ppha_2579 | Ppha_2837 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cch:Cag_0226 8-amino-7-oxononanoate synthase. | PFAM: protein of unknown function DUF452; KEGG: plt:Plut_2068 hypothetical protein. | 0.906 |
Ppha_2579 | Ppha_2838 | Ppha_2579 | Ppha_2838 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cch:Cag_0226 8-amino-7-oxononanoate synthase. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: plt:Plut_2069 8-amino-7-oxononanoate synthase. | 0.922 |
Ppha_2579 | bioA | Ppha_2579 | Ppha_2834 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cch:Cag_0226 8-amino-7-oxononanoate synthase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.961 |
Ppha_2579 | bioB | Ppha_2579 | Ppha_2839 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cch:Cag_0226 8-amino-7-oxononanoate synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.586 |
Ppha_2579 | bioD | Ppha_2579 | Ppha_2835 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cch:Cag_0226 8-amino-7-oxononanoate synthase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.742 |
Ppha_2579 | birA | Ppha_2579 | Ppha_2840 | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cch:Cag_0226 8-amino-7-oxononanoate synthase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.479 |
Ppha_2789 | bioA | Ppha_2789 | Ppha_2834 | Glycine C-acetyltransferase; PFAM: Orn/Lys/Arg decarboxylase major region; aminotransferase class I and II; aminotransferase class-III; KEGG: csc:Csac_1225 glycine C-acetyltransferase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.652 |
Ppha_2789 | bioB | Ppha_2789 | Ppha_2839 | Glycine C-acetyltransferase; PFAM: Orn/Lys/Arg decarboxylase major region; aminotransferase class I and II; aminotransferase class-III; KEGG: csc:Csac_1225 glycine C-acetyltransferase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.621 |
Ppha_2789 | bioD | Ppha_2789 | Ppha_2835 | Glycine C-acetyltransferase; PFAM: Orn/Lys/Arg decarboxylase major region; aminotransferase class I and II; aminotransferase class-III; KEGG: csc:Csac_1225 glycine C-acetyltransferase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.781 |
Ppha_2789 | birA | Ppha_2789 | Ppha_2840 | Glycine C-acetyltransferase; PFAM: Orn/Lys/Arg decarboxylase major region; aminotransferase class I and II; aminotransferase class-III; KEGG: csc:Csac_1225 glycine C-acetyltransferase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.479 |
Ppha_2833 | Ppha_2837 | Ppha_2833 | Ppha_2837 | PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase. | PFAM: protein of unknown function DUF452; KEGG: plt:Plut_2068 hypothetical protein. | 0.523 |
Ppha_2833 | Ppha_2838 | Ppha_2833 | Ppha_2838 | PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: plt:Plut_2069 8-amino-7-oxononanoate synthase. | 0.558 |
Ppha_2833 | bioA | Ppha_2833 | Ppha_2834 | PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase. | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Catalyzes the transfer of the alpha-amino group from S- adenosyl-L-methionine (SAM) to 7-keto-8-aminopelargonic acid (KAPA) to form 7,8-diaminopelargonic acid (DAPA). It is the only animotransferase known to utilize SAM as an amino donor; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. BioA subfamily. | 0.608 |
Ppha_2833 | bioB | Ppha_2833 | Ppha_2839 | PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.528 |
Ppha_2833 | bioC | Ppha_2833 | Ppha_2836 | PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase. | Biotin biosynthesis protein BioC; Converts the free carboxyl group of a malonyl-thioester to its methyl ester by transfer of a methyl group from S-adenosyl-L- methionine (SAM). It allows to synthesize pimeloyl-ACP via the fatty acid synthetic pathway. | 0.523 |
Ppha_2833 | bioD | Ppha_2833 | Ppha_2835 | PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.554 |
Ppha_2833 | birA | Ppha_2833 | Ppha_2840 | PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase. | biotin/acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a repressor; Belongs to the biotin--protein ligase family. | 0.581 |
Ppha_2837 | Ppha_2579 | Ppha_2837 | Ppha_2579 | PFAM: protein of unknown function DUF452; KEGG: plt:Plut_2068 hypothetical protein. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class V; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase class I and II; aminotransferase class-III; KEGG: cch:Cag_0226 8-amino-7-oxononanoate synthase. | 0.906 |
Ppha_2837 | Ppha_2833 | Ppha_2837 | Ppha_2833 | PFAM: protein of unknown function DUF452; KEGG: plt:Plut_2068 hypothetical protein. | PFAM: AMP-dependent synthetase and ligase; KEGG: cph:Cpha266_2588 AMP-dependent synthetase and ligase. | 0.523 |
Ppha_2837 | Ppha_2838 | Ppha_2837 | Ppha_2838 | PFAM: protein of unknown function DUF452; KEGG: plt:Plut_2068 hypothetical protein. | 8-amino-7-oxononanoate synthase; PFAM: aminotransferase class I and II; aminotransferase class-III; KEGG: plt:Plut_2069 8-amino-7-oxononanoate synthase. | 0.984 |