| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| Ppha_1148 | Ppha_2643 | Ppha_1148 | Ppha_2643 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cch:Cag_1081 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | 0.924 |
| Ppha_1148 | Ppha_2895 | Ppha_1148 | Ppha_2895 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cch:Cag_1081 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | 0.504 |
| Ppha_1148 | Ppha_2899 | Ppha_1148 | Ppha_2899 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cch:Cag_1081 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cph:Cpha266_2727 peptidoglycan glycosyltransferase. | 0.947 |
| Ppha_1148 | mtgA | Ppha_1148 | Ppha_2700 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cch:Cag_1081 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.935 |
| Ppha_1148 | murF | Ppha_1148 | Ppha_2898 | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cch:Cag_1081 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.612 |
| Ppha_2643 | Ppha_1148 | Ppha_2643 | Ppha_1148 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | Serine-type D-Ala-D-Ala carboxypeptidase; PFAM: peptidase S11 D-alanyl-D-alanine carboxypeptidase 1; KEGG: cch:Cag_1081 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | 0.924 |
| Ppha_2643 | Ppha_2895 | Ppha_2643 | Ppha_2895 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | 0.530 |
| Ppha_2643 | Ppha_2899 | Ppha_2643 | Ppha_2899 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cph:Cpha266_2727 peptidoglycan glycosyltransferase. | 0.957 |
| Ppha_2643 | mtgA | Ppha_2643 | Ppha_2700 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | Monofunctional biosynthetic peptidoglycan transglycosylase; Peptidoglycan polymerase that catalyzes glycan chain elongation from lipid-linked precursors; Belongs to the glycosyltransferase 51 family. | 0.945 |
| Ppha_2643 | murC | Ppha_2643 | Ppha_2893 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.611 |
| Ppha_2643 | murD | Ppha_2643 | Ppha_2896 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.479 |
| Ppha_2643 | murF | Ppha_2643 | Ppha_2898 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.589 |
| Ppha_2643 | murG | Ppha_2643 | Ppha_2894 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.562 |
| Ppha_2643 | rodA | Ppha_2643 | Ppha_0457 | TIGRFAM: penicillin-binding protein, 1A family; PFAM: glycosyl transferase family 51; penicillin-binding protein transpeptidase; KEGG: cch:Cag_0590 penicillin-binding protein 1A. | Rod shape-determining protein RodA; Peptidoglycan polymerase that is essential for cell wall elongation; Belongs to the SEDS family. MrdB/RodA subfamily. | 0.702 |
| Ppha_2892 | Ppha_2895 | Ppha_2892 | Ppha_2895 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | PFAM: cell cycle protein; KEGG: cph:Cpha266_2722 cell cycle protein; Belongs to the SEDS family. | 0.966 |
| Ppha_2892 | Ppha_2899 | Ppha_2892 | Ppha_2899 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | Peptidoglycan glycosyltransferase; PFAM: penicillin-binding protein transpeptidase; Penicillin-binding protein dimerisation domain; PASTA domain containing protein; KEGG: cph:Cpha266_2727 peptidoglycan glycosyltransferase. | 0.943 |
| Ppha_2892 | murC | Ppha_2892 | Ppha_2893 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramate/alanine ligase; Cell wall formation; Belongs to the MurCDEF family. | 0.945 |
| Ppha_2892 | murD | Ppha_2892 | Ppha_2896 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramoylalanine/D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.956 |
| Ppha_2892 | murF | Ppha_2892 | Ppha_2898 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | UDP-N-acetylmuramyl-tripeptide synthetase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.984 |
| Ppha_2892 | murG | Ppha_2892 | Ppha_2894 | Polypeptide-transport-associated domain protein FtsQ-type; Essential cell division protein. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.981 |