STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Ppha_2917SEFIR domain protein; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SEFIR domain protein; SMART: Tetratricopeptide domain protein; KEGG: nwi:Nwi_3004 TPR repeat protein. (1611 aa)    
Predicted Functional Partners:
Ppha_1253
PFAM: WD-40 repeat protein; KEGG: dar:Daro_3599 WD-40 repeat.
 
 
 0.760
Ppha_0373
PFAM: WD-40 repeat protein; KEGG: cch:Cag_0213 WD-40 repeat.
 
 
 0.754
Ppha_2249
Non-canonical purine NTP pyrophosphatase, rdgB/HAM1 family; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family.
   
   0.745
Ppha_0273
SMART: TIR protein; KEGG: fal:FRAAL5311 hypothetical protein; putative transmembrane receptor activity.
 
 
 0.727
Ppha_2873
SEFIR domain protein; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SEFIR domain protein; SMART: Tetratricopeptide domain protein; KEGG: rru:Rru_A1817 TPR repeat.
  
     0.658
Ppha_0735
PFAM: metallophosphoesterase; protein of unknown function DUF323; NACHT nucleoside triphosphatase; KEGG: cph:Cpha266_1893 protein of unknown function DUF323.
 
 
   0.604
Ppha_0635
Cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporter; PFAM: cyclic nucleotide-binding; ABC transporter transmembrane region; ABC transporter related; SMART: AAA ATPase; KEGG: cph:Cpha266_1843 cyclic nucleotide-regulated ABC bacteriocin/lantibiotic exporters.
 
 
 
 0.596
Ppha_2349
PFAM: metallophosphoesterase; protein of unknown function DUF323; NACHT nucleoside triphosphatase; KEGG: cph:Cpha266_1893 protein of unknown function DUF323.
 
 
   0.576
Ppha_1565
Putative signal transduction protein with Nacht domain; PFAM: protein of unknown function DUF323; NACHT nucleoside triphosphatase; KEGG: cph:Cpha266_1893 protein of unknown function DUF323.
 
     0.572
Ppha_1553
Putative signal transduction protein with Nacht domain; PFAM: protein of unknown function DUF323; NACHT nucleoside triphosphatase; KEGG: cph:Cpha266_0457 putative signal transduction protein with NACHT domain.
 
     0.562
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.