Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Ppha_2919PFAM: ROK family protein; KEGG: cph:Cpha266_2738 N-acetylglucosamine kinase. (304 aa)    
Predicted Functional Partners:
Ppha_2289
KEGG: cch:Cag_0518 mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; TIGRFAM: mannose-1-phosphate guanylyltransferase/mannose-6-phosphate isomerase; PFAM: mannose-6-phosphate isomerase type II; Nucleotidyl transferase; Cupin 2 conserved barrel domain protein.
    
 0.937
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: cph:Cpha266_1095 glucose-6-phosphate isomerase; Belongs to the GPI family.
    
 0.916
glmS
Glucosamine/fructose-6-phosphate aminotransferase, isomerizing; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
  
 
 0.914
Ppha_0392
Putative PTS IIA-like nitrogen-regulatory protein PtsN; PFAM: phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; KEGG: plt:Plut_1787 putative PTS IIA-like nitrogen-regulatory protein PtsN.
   
 
 0.911
Ppha_0717
PFAM: phosphofructokinase; KEGG: cch:Cag_1780 phosphofructokinase.
    
 0.910
pfkA
6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis.
    
 0.910
fbp
PFAM: Inositol phosphatase/fructose-16-bisphosphatase; KEGG: cph:Cpha266_0686 fructose-1,6-bisphosphatase.
     
  0.900
yidC
60 kDa inner membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
    0.787
Ppha_2920
PFAM: phosphoesterase PA-phosphatase related; KEGG: pvi:Cvib_1770 phosphoesterase, PA-phosphatase related.
       0.786
Ppha_2922
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
       0.786
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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