Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
rnpARibonuclease P; RNaseP catalyzes the removal of the 5'-leader sequence from pre-tRNA to produce the mature 5'-terminus. It can also cleave other RNA substrates such as 4.5S RNA. The protein component plays an auxiliary but essential role in vivo by binding to the 5'-leader sequence and broadening the substrate specificity of the ribozyme. (136 aa)    
Predicted Functional Partners:
rpmH
PFAM: ribosomal protein L34; KEGG: cph:Cpha266_2743 50S ribosomal protein L34; Belongs to the bacterial ribosomal protein bL34 family.
  
  
 0.971
Ppha_2922
Protein of unknown function DUF37; Could be involved in insertion of integral membrane proteins into the membrane; Belongs to the UPF0161 family.
  
  
 0.970
yidC
60 kDa inner membrane insertion protein; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins.
  
  
 0.931
rplD
Ribosomal protein L4/L1e; Forms part of the polypeptide exit tunnel.
   
  
 0.802
rplC
Ribosomal protein L3; One of the primary rRNA binding proteins, it binds directly near the 3'-end of the 23S rRNA, where it nucleates assembly of the 50S subunit; Belongs to the universal ribosomal protein uL3 family.
   
  
 0.786
Ppha_0452
PFAM: RNA binding S1 domain protein; KEGG: cch:Cag_0570 30S ribosomal protein S1.
  
  
 0.779
rpsP
PFAM: ribosomal protein S16; KEGG: cph:Cpha266_1524 30S ribosomal protein S16; Belongs to the bacterial ribosomal protein bS16 family.
   
  
 0.772
rpmB
PFAM: ribosomal protein L28; KEGG: cph:Cpha266_0582 50S ribosomal protein L28; Belongs to the bacterial ribosomal protein bL28 family.
  
  
 0.770
rpsT
Ribosomal protein S20; Binds directly to 16S ribosomal RNA.
  
    0.769
rpsJ
Ribosomal protein S10; Involved in the binding of tRNA to the ribosomes. Belongs to the universal ribosomal protein uS10 family.
   
    0.767
Your Current Organism:
Pelodictyon phaeoclathratiforme
NCBI taxonomy Id: 324925
Other names: P. phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme BU-1, Pelodictyon phaeoclathratiforme DSM 5477, Pelodictyon phaeoclathratiforme str. BU-1, Pelodictyon phaeoclathratiforme strain BU-1
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