node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sbal_1092 | Sbal_1759 | Sbal_1092 | Sbal_1759 | PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase. | 0.685 |
Sbal_1092 | Sbal_1760 | Sbal_1092 | Sbal_1760 | PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2429 biotin biosynthesis protein BioC. | 0.448 |
Sbal_1092 | bioB | Sbal_1092 | Sbal_1758 | PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.885 |
Sbal_1092 | bioD | Sbal_1092 | Sbal_1761 | PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.898 |
Sbal_1092 | birA | Sbal_1092 | Sbal_4174 | PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.478 |
Sbal_1092 | kbl | Sbal_1092 | Sbal_0058 | PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.679 |
Sbal_1757 | Sbal_1759 | Sbal_1757 | Sbal_1759 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase. | 0.990 |
Sbal_1757 | Sbal_1760 | Sbal_1757 | Sbal_1760 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2429 biotin biosynthesis protein BioC. | 0.558 |
Sbal_1757 | bioB | Sbal_1757 | Sbal_1758 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.990 |
Sbal_1757 | bioD | Sbal_1757 | Sbal_1761 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.997 |
Sbal_1757 | birA | Sbal_1757 | Sbal_4174 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.478 |
Sbal_1757 | kbl | Sbal_1757 | Sbal_0058 | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 2-amino-3-ketobutyrate coenzyme A ligase; Catalyzes the cleavage of 2-amino-3-ketobutyrate to glycine and acetyl-CoA. | 0.728 |
Sbal_1759 | Sbal_1092 | Sbal_1759 | Sbal_1092 | 8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase. | PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.685 |
Sbal_1759 | Sbal_1757 | Sbal_1759 | Sbal_1757 | 8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase. | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.990 |
Sbal_1759 | Sbal_1760 | Sbal_1759 | Sbal_1760 | 8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase. | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2429 biotin biosynthesis protein BioC. | 0.915 |
Sbal_1759 | bioB | Sbal_1759 | Sbal_1758 | 8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase. | Biotin synthase; Catalyzes the conversion of dethiobiotin (DTB) to biotin by the insertion of a sulfur atom into dethiobiotin via a radical-based mechanism; Belongs to the radical SAM superfamily. Biotin synthase family. | 0.940 |
Sbal_1759 | bioD | Sbal_1759 | Sbal_1761 | 8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase. | Dethiobiotin synthase; Catalyzes a mechanistically unusual reaction, the ATP- dependent insertion of CO2 between the N7 and N8 nitrogen atoms of 7,8- diaminopelargonic acid (DAPA) to form an ureido ring. | 0.977 |
Sbal_1759 | birA | Sbal_1759 | Sbal_4174 | 8-amino-7-oxononanoate synthase; PFAM: Cys/Met metabolism pyridoxal-phosphate-dependent enzymes; aromatic amino acid beta-eliminating lyase/threonine aldolase; aminotransferase, class I and II; aminotransferase class-III; KEGG: shm:Shewmr7_2430 8-amino-7-oxononanoate synthase. | biotin--acetyl-CoA-carboxylase ligase; Acts both as a biotin--[acetyl-CoA-carboxylase] ligase and a biotin-operon repressor. In the presence of ATP, BirA activates biotin to form the BirA-biotinyl-5'-adenylate (BirA-bio-5'-AMP or holoBirA) complex. HoloBirA can either transfer the biotinyl moiety to the biotin carboxyl carrier protein (BCCP) subunit of acetyl-CoA carboxylase, or bind to the biotin operator site and inhibit transcription of the operon. | 0.487 |
Sbal_1760 | Sbal_1092 | Sbal_1760 | Sbal_1092 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2429 biotin biosynthesis protein BioC. | PFAM: aminotransferase class-III; KEGG: she:Shewmr4_2927 aminotransferase class-III; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.448 |
Sbal_1760 | Sbal_1757 | Sbal_1760 | Sbal_1757 | PFAM: Methyltransferase type 11; Methyltransferase type 12; KEGG: shm:Shewmr7_2429 biotin biosynthesis protein BioC. | Aminotransferase; TIGRFAM: adenosylmethionine-8-amino-7-oxononanoate aminotransferase; PFAM: aminotransferase class-III; KEGG: son:SO2741 adenosylmethionine-8-amino-7-oxononanoate aminotransferase; Belongs to the class-III pyridoxal-phosphate-dependent aminotransferase family. | 0.558 |