node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_0182 | Sama_0252 | Sama_0182 | Sama_0252 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | KEGG: son:SO0272 competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.918 |
Sama_0182 | Sama_0285 | Sama_0182 | Sama_0285 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | KEGG: son:SO0372 HAD-superfamily hydrolase, subfamily IA, variant 1 protein family. | 0.914 |
Sama_0182 | Sama_2419 | Sama_0182 | Sama_2419 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | KEGG: son:SO1550 hypothetical protein. | 0.913 |
Sama_0182 | add | Sama_0182 | Sama_0085 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | KEGG: son:SO4731 adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.910 |
Sama_0182 | cpdA | Sama_0182 | Sama_3045 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | lacZ expression regulator; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.914 |
Sama_0182 | guaA | Sama_0182 | Sama_2358 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.917 |
Sama_0182 | guaB | Sama_0182 | Sama_2359 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | Inosine-5'-monophosphate dehydrogenase; Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Belongs to the IMPDH/GMPR family. | 0.920 |
Sama_0182 | nadD | Sama_0182 | Sama_2585 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.910 |
Sama_0182 | ppnP | Sama_0182 | Sama_3424 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions. | 0.913 |
Sama_0182 | surE | Sama_0182 | Sama_1041 | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | 3'-nucleotidase / exopolyphosphatase / 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.909 |
Sama_0252 | Sama_0182 | Sama_0252 | Sama_0182 | KEGG: son:SO0272 competence/damage-inducible protein CinA; Belongs to the CinA family. | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | 0.918 |
Sama_0252 | Sama_0285 | Sama_0252 | Sama_0285 | KEGG: son:SO0272 competence/damage-inducible protein CinA; Belongs to the CinA family. | KEGG: son:SO0372 HAD-superfamily hydrolase, subfamily IA, variant 1 protein family. | 0.918 |
Sama_0252 | nadD | Sama_0252 | Sama_2585 | KEGG: son:SO0272 competence/damage-inducible protein CinA; Belongs to the CinA family. | Nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD). | 0.974 |
Sama_0252 | surE | Sama_0252 | Sama_1041 | KEGG: son:SO0272 competence/damage-inducible protein CinA; Belongs to the CinA family. | 3'-nucleotidase / exopolyphosphatase / 5'-nucleotidase; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.918 |
Sama_0285 | Sama_0182 | Sama_0285 | Sama_0182 | KEGG: son:SO0372 HAD-superfamily hydrolase, subfamily IA, variant 1 protein family. | KEGG: son:SO0177 HAD-superfamily hydrolase, subfamily IA, variant 3 protein family. | 0.914 |
Sama_0285 | Sama_0252 | Sama_0285 | Sama_0252 | KEGG: son:SO0372 HAD-superfamily hydrolase, subfamily IA, variant 1 protein family. | KEGG: son:SO0272 competence/damage-inducible protein CinA; Belongs to the CinA family. | 0.918 |
Sama_0285 | Sama_2419 | Sama_0285 | Sama_2419 | KEGG: son:SO0372 HAD-superfamily hydrolase, subfamily IA, variant 1 protein family. | KEGG: son:SO1550 hypothetical protein. | 0.901 |
Sama_0285 | add | Sama_0285 | Sama_0085 | KEGG: son:SO0372 HAD-superfamily hydrolase, subfamily IA, variant 1 protein family. | KEGG: son:SO4731 adenosine deaminase; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily. | 0.929 |
Sama_0285 | cpdA | Sama_0285 | Sama_3045 | KEGG: son:SO0372 HAD-superfamily hydrolase, subfamily IA, variant 1 protein family. | lacZ expression regulator; Hydrolyzes cAMP to 5'-AMP. Plays an important regulatory role in modulating the intracellular concentration of cAMP, thereby influencing cAMP-dependent processes. | 0.901 |
Sama_0285 | guaA | Sama_0285 | Sama_2358 | KEGG: son:SO0372 HAD-superfamily hydrolase, subfamily IA, variant 1 protein family. | GMP synthase (glutamine-hydrolyzing); Catalyzes the synthesis of GMP from XMP. | 0.917 |