node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_0367 | Sama_0368 | Sama_0367 | Sama_0368 | Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | KEGG: son:SO0415 type IV pilus biogenesis protein PilC. | 0.964 |
Sama_0367 | coaE | Sama_0367 | Sama_0366 | Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.881 |
Sama_0367 | yacG | Sama_0367 | Sama_0364 | Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.641 |
Sama_0367 | zapD | Sama_0367 | Sama_0365 | Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.834 |
Sama_0368 | Sama_0367 | Sama_0368 | Sama_0367 | KEGG: son:SO0415 type IV pilus biogenesis protein PilC. | Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.964 |
Sama_0368 | coaE | Sama_0368 | Sama_0366 | KEGG: son:SO0415 type IV pilus biogenesis protein PilC. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.679 |
Sama_0368 | yacG | Sama_0368 | Sama_0364 | KEGG: son:SO0415 type IV pilus biogenesis protein PilC. | Conserved hypothetical protein; Inhibits all the catalytic activities of DNA gyrase by preventing its interaction with DNA. Acts by binding directly to the C- terminal domain of GyrB, which probably disrupts DNA binding by the gyrase. | 0.533 |
Sama_0368 | zapD | Sama_0368 | Sama_0365 | KEGG: son:SO0415 type IV pilus biogenesis protein PilC. | Conserved hypothetical protein; Cell division factor that enhances FtsZ-ring assembly. Directly interacts with FtsZ and promotes bundling of FtsZ protofilaments, with a reduction in FtsZ GTPase activity. | 0.676 |
Sama_1034 | coaE | Sama_1034 | Sama_0366 | KEGG: son:SO3442 MazG family protein. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.903 |
Sama_1119 | coaE | Sama_1119 | Sama_0366 | Phosphopantetheinyl transferase-like protein; KEGG: sdn:Sden_2625 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.903 |
Sama_2993 | coaE | Sama_2993 | Sama_0366 | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.642 |
acpS | coaE | Sama_0884 | Sama_0366 | Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.905 |
coaD | coaE | Sama_0110 | Sama_0366 | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | 0.967 |
coaE | Sama_0367 | Sama_0366 | Sama_0367 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Type 4 prepilin peptidase 1. Aspartic peptidase. MEROPS family A24A; Cleaves type-4 fimbrial leader sequence and methylates the N- terminal (generally Phe) residue. | 0.881 |
coaE | Sama_0368 | Sama_0366 | Sama_0368 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | KEGG: son:SO0415 type IV pilus biogenesis protein PilC. | 0.679 |
coaE | Sama_1034 | Sama_0366 | Sama_1034 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | KEGG: son:SO3442 MazG family protein. | 0.903 |
coaE | Sama_1119 | Sama_0366 | Sama_1119 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Phosphopantetheinyl transferase-like protein; KEGG: sdn:Sden_2625 4'-phosphopantetheinyl transferase; Belongs to the P-Pant transferase superfamily. | 0.903 |
coaE | Sama_2993 | Sama_0366 | Sama_2993 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Translation factor SUA5; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. | 0.642 |
coaE | acpS | Sama_0366 | Sama_0884 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Holo-(acyl-carrier-protein) synthase; Transfers the 4'-phosphopantetheine moiety from coenzyme A to a Ser of acyl-carrier-protein; Belongs to the P-Pant transferase superfamily. AcpS family. | 0.905 |
coaE | coaD | Sama_0366 | Sama_0110 | Dephospho-CoA kinase; Catalyzes the phosphorylation of the 3'-hydroxyl group of dephosphocoenzyme A to form coenzyme A; Belongs to the CoaE family. | Pantetheine-phosphate adenylyltransferase; Reversibly transfers an adenylyl group from ATP to 4'- phosphopantetheine, yielding dephospho-CoA (dPCoA) and pyrophosphate. Belongs to the bacterial CoaD family. | 0.967 |