node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_0978 | Sama_1325 | Sama_0978 | Sama_1325 | KEGG: son:SO1223 phosphoserine phosphatase. | KEGG: son:SO2248 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.910 |
Sama_0978 | Sama_1747 | Sama_0978 | Sama_1747 | KEGG: son:SO1223 phosphoserine phosphatase. | KEGG: son:SO2390 CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.903 |
Sama_0978 | Sama_2600 | Sama_0978 | Sama_2600 | KEGG: son:SO1223 phosphoserine phosphatase. | KEGG: son:SO3575 CDP-diacylglycerol--serine O-phosphatidyltransferase, putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.906 |
Sama_0978 | glyA | Sama_0978 | Sama_1014 | KEGG: son:SO1223 phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.944 |
Sama_0978 | ilvA | Sama_0978 | Sama_3278 | KEGG: son:SO1223 phosphoserine phosphatase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.916 |
Sama_0978 | trpA | Sama_0978 | Sama_2134 | KEGG: son:SO1223 phosphoserine phosphatase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.903 |
Sama_0978 | trpB | Sama_0978 | Sama_2133 | KEGG: son:SO1223 phosphoserine phosphatase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.921 |
Sama_1144 | Sama_1609 | Sama_1144 | Sama_1609 | KEGG: sdn:Sden_1559 phosphatidate cytidylyltransferase; Belongs to the CDS family. | KEGG: son:SO1862 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.952 |
Sama_1144 | Sama_1747 | Sama_1144 | Sama_1747 | KEGG: sdn:Sden_1559 phosphatidate cytidylyltransferase; Belongs to the CDS family. | KEGG: son:SO2390 CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.913 |
Sama_1144 | Sama_2600 | Sama_1144 | Sama_2600 | KEGG: sdn:Sden_1559 phosphatidate cytidylyltransferase; Belongs to the CDS family. | KEGG: son:SO3575 CDP-diacylglycerol--serine O-phosphatidyltransferase, putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.940 |
Sama_1144 | psd | Sama_1144 | Sama_3034 | KEGG: sdn:Sden_1559 phosphatidate cytidylyltransferase; Belongs to the CDS family. | Phosphatidylserine decarboxylase; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.448 |
Sama_1325 | Sama_0978 | Sama_1325 | Sama_0978 | KEGG: son:SO2248 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | KEGG: son:SO1223 phosphoserine phosphatase. | 0.910 |
Sama_1325 | Sama_1747 | Sama_1325 | Sama_1747 | KEGG: son:SO2248 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | KEGG: son:SO2390 CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.900 |
Sama_1325 | Sama_2600 | Sama_1325 | Sama_2600 | KEGG: son:SO2248 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | KEGG: son:SO3575 CDP-diacylglycerol--serine O-phosphatidyltransferase, putative; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
Sama_1325 | glyA | Sama_1325 | Sama_1014 | KEGG: son:SO2248 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.944 |
Sama_1325 | ilvA | Sama_1325 | Sama_3278 | KEGG: son:SO2248 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.919 |
Sama_1325 | trpA | Sama_1325 | Sama_2134 | KEGG: son:SO2248 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.901 |
Sama_1325 | trpB | Sama_1325 | Sama_2133 | KEGG: son:SO2248 L-serine dehydratase 1; Belongs to the iron-sulfur dependent L-serine dehydratase family. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.900 |
Sama_1609 | Sama_1144 | Sama_1609 | Sama_1144 | KEGG: son:SO1862 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | KEGG: sdn:Sden_1559 phosphatidate cytidylyltransferase; Belongs to the CDS family. | 0.952 |
Sama_1609 | Sama_1747 | Sama_1609 | Sama_1747 | KEGG: son:SO1862 CDP-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | KEGG: son:SO2390 CDP-diacylglycerol--serine O-phosphatidyltransferase. | 0.918 |