node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_0978 | glyA | Sama_0978 | Sama_1014 | KEGG: son:SO1223 phosphoserine phosphatase. | Serine hydroxymethyltransferase; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.944 |
Sama_0978 | ilvA | Sama_0978 | Sama_3278 | KEGG: son:SO1223 phosphoserine phosphatase. | L-threonine ammonia-lyase; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the second step is accelerated by RidA. | 0.916 |
Sama_0978 | trpA | Sama_0978 | Sama_2134 | KEGG: son:SO1223 phosphoserine phosphatase. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.903 |
Sama_0978 | trpB | Sama_0978 | Sama_2133 | KEGG: son:SO1223 phosphoserine phosphatase. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.921 |
Sama_1687 | Sama_2129 | Sama_1687 | Sama_2129 | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | KEGG: son:SO3019 anthranilate synthase component I. | 0.851 |
Sama_1687 | Sama_2130 | Sama_1687 | Sama_2130 | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | Anthranilate synthase, component II; KEGG: sdn:Sden_2451 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | 0.999 |
Sama_1687 | Sama_3015 | Sama_1687 | Sama_3015 | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | Aminodeoxychorismate synthase, glutamine amidotransferase subunit; KEGG: son:SO0613 para-aminobenzoate synthase glutamine amidotransferase, component II. | 0.999 |
Sama_1687 | trpA | Sama_1687 | Sama_2134 | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.921 |
Sama_1687 | trpB | Sama_1687 | Sama_2133 | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.924 |
Sama_1687 | trpD | Sama_1687 | Sama_2131 | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.984 |
Sama_1687 | trpF | Sama_1687 | Sama_2132 | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | KEGG: son:SO3022 indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family. | 0.999 |
Sama_2129 | Sama_1687 | Sama_2129 | Sama_1687 | KEGG: son:SO3019 anthranilate synthase component I. | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | 0.851 |
Sama_2129 | Sama_2130 | Sama_2129 | Sama_2130 | KEGG: son:SO3019 anthranilate synthase component I. | Anthranilate synthase, component II; KEGG: sdn:Sden_2451 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | 0.999 |
Sama_2129 | Sama_3015 | Sama_2129 | Sama_3015 | KEGG: son:SO3019 anthranilate synthase component I. | Aminodeoxychorismate synthase, glutamine amidotransferase subunit; KEGG: son:SO0613 para-aminobenzoate synthase glutamine amidotransferase, component II. | 0.999 |
Sama_2129 | trpA | Sama_2129 | Sama_2134 | KEGG: son:SO3019 anthranilate synthase component I. | Tryptophan synthase, alpha chain; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.973 |
Sama_2129 | trpB | Sama_2129 | Sama_2133 | KEGG: son:SO3019 anthranilate synthase component I. | Tryptophan synthase, beta chain; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.969 |
Sama_2129 | trpD | Sama_2129 | Sama_2131 | KEGG: son:SO3019 anthranilate synthase component I. | Anthranilate phosphoribosyltransferase; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.999 |
Sama_2129 | trpF | Sama_2129 | Sama_2132 | KEGG: son:SO3019 anthranilate synthase component I. | KEGG: son:SO3022 indole-3-glycerol phosphate synthase/phosphoribosylanthranilate isomerase; Belongs to the TrpC family. | 0.999 |
Sama_2130 | Sama_1687 | Sama_2130 | Sama_1687 | Anthranilate synthase, component II; KEGG: sdn:Sden_2451 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | KEGG: son:SO2221 para-aminobenzoate synthase, component I. | 0.999 |
Sama_2130 | Sama_2129 | Sama_2130 | Sama_2129 | Anthranilate synthase, component II; KEGG: sdn:Sden_2451 glutamine amidotransferase of anthranilate synthase or para-aminobenzoate synthase. | KEGG: son:SO3019 anthranilate synthase component I. | 0.999 |