node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_0376 | Sama_0377 | Sama_0376 | Sama_0377 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | 0.999 |
Sama_0376 | Sama_2795 | Sama_0376 | Sama_2795 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Branched-chain alpha-keto acid dehydrogenase E1 component; KEGG: sdn:Sden_3017 transketolase, central region. | 0.999 |
Sama_0376 | gcvH | Sama_0376 | Sama_2720 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.607 |
Sama_0376 | gcvP | Sama_0376 | Sama_2719 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.628 |
Sama_0376 | lipA | Sama_0376 | Sama_2595 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.513 |
Sama_0376 | lipB | Sama_0376 | Sama_2594 | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.646 |
Sama_0377 | Sama_0376 | Sama_0377 | Sama_0376 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | Dihydrolipoyllysine-residue succinyltransferase; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). | 0.999 |
Sama_0377 | Sama_1428 | Sama_0377 | Sama_1428 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | 0.998 |
Sama_0377 | Sama_2795 | Sama_0377 | Sama_2795 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | Branched-chain alpha-keto acid dehydrogenase E1 component; KEGG: sdn:Sden_3017 transketolase, central region. | 0.999 |
Sama_0377 | gcvH | Sama_0377 | Sama_2720 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.976 |
Sama_0377 | gcvP | Sama_0377 | Sama_2719 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.949 |
Sama_0377 | lipA | Sama_0377 | Sama_2595 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.620 |
Sama_0377 | lipB | Sama_0377 | Sama_2594 | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.528 |
Sama_1428 | Sama_0377 | Sama_1428 | Sama_0377 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | KEGG: sdn:Sden_3381 dihydrolipoamide dehydrogenase. | 0.998 |
Sama_1428 | Sama_2795 | Sama_1428 | Sama_2795 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Branched-chain alpha-keto acid dehydrogenase E1 component; KEGG: sdn:Sden_3017 transketolase, central region. | 0.999 |
Sama_1428 | gcvH | Sama_1428 | Sama_2720 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Glycine cleavage system H protein; The glycine cleavage system catalyzes the degradation of glycine. The H protein shuttles the methylamine group of glycine from the P protein to the T protein. | 0.607 |
Sama_1428 | gcvP | Sama_1428 | Sama_2719 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.628 |
Sama_1428 | lipA | Sama_1428 | Sama_2595 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Lipoic acid synthetase; Catalyzes the radical-mediated insertion of two sulfur atoms into the C-6 and C-8 positions of the octanoyl moiety bound to the lipoyl domains of lipoate-dependent enzymes, thereby converting the octanoylated domains into lipoylated derivatives. | 0.531 |
Sama_1428 | lipB | Sama_1428 | Sama_2594 | 2-oxoglutarate dehydrogenase E2 component; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2). | Lipoate-protein ligase B; Catalyzes the transfer of endogenously produced octanoic acid from octanoyl-acyl-carrier-protein onto the lipoyl domains of lipoate- dependent enzymes. Lipoyl-ACP can also act as a substrate although octanoyl-ACP is likely to be the physiological substrate. | 0.522 |
Sama_2592 | Sama_2593 | Sama_2592 | Sama_2593 | Penicillin-binding protein 6. Serine peptidase. MEROPS family S11; KEGG: son:SO1164 D-alanyl-D-alanine carboxypeptidase; Belongs to the peptidase S11 family. | KEGG: son:SO1163 hypothetical protein; Belongs to the UPF0250 family. | 0.593 |