node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
Sama_1294 | Sama_1298 | Sama_1294 | Sama_1298 | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | 0.989 |
Sama_1294 | Sama_1506 | Sama_1294 | Sama_1506 | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; KEGG: cps:CPS_0838 aminotransferase, class V. | 0.987 |
Sama_1294 | cyaY | Sama_1294 | Sama_3252 | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.983 |
Sama_1294 | hscA | Sama_1294 | Sama_1297 | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.987 |
Sama_1294 | hscB | Sama_1294 | Sama_1296 | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.998 |
Sama_1294 | iscS | Sama_1294 | Sama_1293 | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.999 |
Sama_1294 | msrA-2 | Sama_1294 | Sama_1991 | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | protein-methionine-S-oxide reductase, PilB family; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine. | 0.402 |
Sama_1294 | nfuA | Sama_1294 | Sama_3502 | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | YhgI protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.979 |
Sama_1298 | Sama_1294 | Sama_1298 | Sama_1294 | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.989 |
Sama_1298 | Sama_1506 | Sama_1298 | Sama_1506 | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | Cysteine desulfurase; KEGG: cps:CPS_0838 aminotransferase, class V. | 0.717 |
Sama_1298 | cyaY | Sama_1298 | Sama_3252 | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.871 |
Sama_1298 | hscA | Sama_1298 | Sama_1297 | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.976 |
Sama_1298 | hscB | Sama_1298 | Sama_1296 | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | Co-chaperone Hsc20; Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family. | 0.987 |
Sama_1298 | iscS | Sama_1298 | Sama_1293 | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | Cysteine desulfurase; Master enzyme that delivers sulfur to a number of partners involved in Fe-S cluster assembly, tRNA modification or cofactor biosynthesis. Catalyzes the removal of elemental sulfur atoms from cysteine to produce alanine. Functions as a sulfur delivery protein for Fe-S cluster synthesis onto IscU, an Fe-S scaffold assembly protein, as well as other S acceptor proteins; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. NifS/IscS subfamily. | 0.975 |
Sama_1298 | nfuA | Sama_1298 | Sama_3502 | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | YhgI protein; Involved in iron-sulfur cluster biogenesis. Binds a 4Fe-4S cluster, can transfer this cluster to apoproteins, and thereby intervenes in the maturation of Fe/S proteins. Could also act as a scaffold/chaperone for damaged Fe/S proteins. | 0.609 |
Sama_1506 | Sama_1294 | Sama_1506 | Sama_1294 | Cysteine desulfurase; KEGG: cps:CPS_0838 aminotransferase, class V. | NifU family protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters. | 0.987 |
Sama_1506 | Sama_1298 | Sama_1506 | Sama_1298 | Cysteine desulfurase; KEGG: cps:CPS_0838 aminotransferase, class V. | KEGG: son:SO2269 ferredoxin, 2Fe-2S. | 0.717 |
Sama_1506 | cyaY | Sama_1506 | Sama_3252 | Cysteine desulfurase; KEGG: cps:CPS_0838 aminotransferase, class V. | CyaY protein; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. | 0.923 |
Sama_1506 | hemH | Sama_1506 | Sama_1316 | Cysteine desulfurase; KEGG: cps:CPS_0838 aminotransferase, class V. | Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.510 |
Sama_1506 | hscA | Sama_1506 | Sama_1297 | Cysteine desulfurase; KEGG: cps:CPS_0838 aminotransferase, class V. | Chaperone protein HscA; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB. | 0.682 |