STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ABB43794.1Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family. (141 aa)    
Predicted Functional Partners:
ABB43793.1
Heat shock protein Hsp20; Belongs to the small heat shock protein (HSP20) family.
 
    
0.795
ABB43738.1
AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.687
ABB43800.1
AAA ATPase; Belongs to the ClpA/ClpB family.
  
 
 0.687
ABB43792.1
Cyclic nucleotide-binding domain (cNMP-BD) protein.
  
  
 0.551
dnaK
Chaperone DnaK; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.533
htpG
Heat shock protein Hsp90; Molecular chaperone. Has ATPase activity.
  
 
 0.532
grpE
GrpE protein; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several rounds of ATP-dependent i [...]
  
  
 0.478
hslV
20S proteasome, A and B subunits; Protease subunit of a proteasome-like degradation complex believed to be a general protein degrading machinery.
   
  
 0.449
ABB43708.1
Conserved hypothetical protein.
 
  
 0.440
msrA
Methionine sulfoxide reductase A/B; Has an important function as a repair enzyme for proteins that have been inactivated by oxidation. Catalyzes the reversible oxidation-reduction of methionine sulfoxide in proteins to methionine.
  
  
 0.420
Your Current Organism:
Sulfurimonas denitrificans
NCBI taxonomy Id: 326298
Other names: S. denitrificans DSM 1251, Sulfurimonas denitrificans DSM 1251, Thiomicrospira denitrificans ATCC 33889
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