STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
FRAAL0045Putative secreted transglycosylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (331 aa)    
Predicted Functional Partners:
FRAAL0044
Hypothetical protein; No homology to any previously reported sequences.
       0.781
amiB
N-acetymuramyl-L-alanine amidase; Function of strongly homologous gene; enzyme.
  
  
 0.690
FRAAL6414
Putative two-component system sensory histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
  
 0.639
FRAAL6455
Putative two-component system sensory histidine kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
  
 0.622
FRAAL4350
Hypothetical protein; No homology to any previously reported sequences.
  
  
 0.591
FRAAL0771
Putative signaling protein with a PAS domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
  
  
 0.588
FRAAL1281
Putative penicillin-binding transpeptidase (partial match); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.580
FRAAL4194
Putative hybrid sensor histidine kinase/response regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
  
  
 0.576
relA1
GTP diphosphokinase / guanosine-3',5'-bis(diphosphate) 3'-diphosphatase; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
 
   0.543
nnrD
Putative ribokinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
  
  
 0.542
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.