STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltACitrate synthase; Function of strongly homologous gene; enzyme; Belongs to the citrate synthase family. (455 aa)    
Predicted Functional Partners:
acnA
Aconitate hydratase 1; Function of strongly homologous gene; enzyme.
 
 0.990
mdh
Malate dehydrogenase; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.979
aceB-2
Malate synthase G; Involved in the glycolate utilization. Catalyzes the condensation and subsequent hydrolysis of acetyl-coenzyme A (acetyl- CoA) and glyoxylate to form malate and CoA; Belongs to the malate synthase family. GlcB subfamily.
  
 0.968
FRAAL3253
Pyruvate-flavodoxin oxidoreductase; Function of strongly homologous gene; enzyme.
  
 0.967
FRAAL0680
Pyruvate carboxylase 2 (Pyruvic carboxylase 2) (PCB 2); Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second.
  
 0.963
acs
acetyl-CoA synthetase, has propionyl-CoA synthetase activity; Function of strongly homologous gene; enzyme.
  
 0.959
aceF
Dihydrolipoamide acyltransferase component; Function of strongly homologous gene; enzyme.
  
 0.946
FRAAL3226
Putative dihydrolipoamide acyltransferase component E2; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.946
aceB
Malate synthase A; Function of strongly homologous gene; enzyme.
  
 0.943
fumC
Fumarase C (fumarate hydratase Class II); Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 0.937
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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