| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FRAAL1005 | FRAAL1008 | FRAAL1005 | FRAAL1008 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.416 |
| FRAAL1005 | ubiA | FRAAL1005 | FRAAL1007 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 4-hydroxybenzoate octaprenyltransferase; Function of strongly homologous gene; enzyme; Belongs to the UbiA prenyltransferase family. | 0.502 |
| FRAAL1005 | ubiD | FRAAL1005 | FRAAL1006 | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Function of strongly homologous gene; enzyme; Belongs to the UbiD family. | 0.545 |
| FRAAL1008 | FRAAL1005 | FRAAL1008 | FRAAL1005 | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Homologs of previously reported genes of unknown function. | 0.416 |
| FRAAL1008 | mqnA | FRAAL1008 | FRAAL1013 | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.760 |
| FRAAL1008 | mqnB | FRAAL1008 | FRAAL6734 | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.505 |
| FRAAL1008 | mqnC | FRAAL1008 | FRAAL1025 | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.746 |
| FRAAL1008 | mqnD | FRAAL1008 | FRAAL6735 | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.720 |
| FRAAL1008 | mqnE | FRAAL1008 | FRAAL1010 | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | Conserved hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.802 |
| FRAAL1008 | ubiA | FRAAL1008 | FRAAL1007 | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 4-hydroxybenzoate octaprenyltransferase; Function of strongly homologous gene; enzyme; Belongs to the UbiA prenyltransferase family. | 0.992 |
| FRAAL1008 | ubiD | FRAAL1008 | FRAAL1006 | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 3-polyprenyl-4-hydroxybenzoate decarboxylase; Function of strongly homologous gene; enzyme; Belongs to the UbiD family. | 0.996 |
| FRAAL2557 | idi | FRAAL2557 | FRAAL6504 | Non-ribosomal peptide synthetase (Fragment); Function of strongly homologous gene; enzyme. | Isopentenyl diphosphate isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 0.634 |
| FRAAL2557 | ubiA | FRAAL2557 | FRAAL1007 | Non-ribosomal peptide synthetase (Fragment); Function of strongly homologous gene; enzyme. | 4-hydroxybenzoate octaprenyltransferase; Function of strongly homologous gene; enzyme; Belongs to the UbiA prenyltransferase family. | 0.575 |
| idi | FRAAL2557 | FRAAL6504 | FRAAL2557 | Isopentenyl diphosphate isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | Non-ribosomal peptide synthetase (Fragment); Function of strongly homologous gene; enzyme. | 0.634 |
| idi | ubiA | FRAAL6504 | FRAAL1007 | Isopentenyl diphosphate isomerase; Catalyzes the 1,3-allylic rearrangement of the homoallylic substrate isopentenyl (IPP) to its highly electrophilic allylic isomer, dimethylallyl diphosphate (DMAPP). | 4-hydroxybenzoate octaprenyltransferase; Function of strongly homologous gene; enzyme; Belongs to the UbiA prenyltransferase family. | 0.547 |
| mqnA | FRAAL1008 | FRAAL1013 | FRAAL1008 | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. | 0.760 |
| mqnA | mqnB | FRAAL1013 | FRAAL6734 | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved hypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.895 |
| mqnA | mqnC | FRAAL1013 | FRAAL1025 | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved hypothetical protein; Radical SAM enzyme that catalyzes the cyclization of dehypoxanthine futalosine (DHFL) into cyclic dehypoxanthine futalosine (CDHFL), a step in the biosynthesis of menaquinone (MK, vitamin K2). | 0.900 |
| mqnA | mqnD | FRAAL1013 | FRAAL6735 | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily. | 0.907 |
| mqnA | mqnE | FRAAL1013 | FRAAL1010 | Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2). | Conserved hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. | 0.993 |