STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
mqnEConserved hypothetical protein; Radical SAM enzyme that catalyzes the addition of the adenosyl radical to the double bond of 3-[(1-carboxyvinyl)oxy]benzoate, leading to aminodeoxyfutalosine (AFL), a key intermediate in the formation of menaquinone (MK, vitamin K2) from chorismate. (390 aa)    
Predicted Functional Partners:
mqnA
Conserved hypothetical protein; Catalyzes the dehydration of chorismate into 3-[(1- carboxyvinyl)oxy]benzoate, a step in the biosynthesis of menaquinone (MK, vitamin K2).
  
 0.995
FRAAL1027
Putative adenosine deaminase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
     
 0.903
ubiA
4-hydroxybenzoate octaprenyltransferase; Function of strongly homologous gene; enzyme; Belongs to the UbiA prenyltransferase family.
 
   
 0.858
mqnD
Conserved hypothetical protein; Catalyzes the conversion of cyclic dehypoxanthine futalosine (cyclic DHFL) into 1,4-dihydroxy-6-naphthoate, a step in the biosynthesis of menaquinone (MK, vitamin K2); Belongs to the MqnA/MqnD family. MqnD subfamily.
 
   
 0.856
mqnB
Conserved hypothetical protein; Catalyzes the hydrolysis of futalosine (FL) to dehypoxanthine futalosine (DHFL) and hypoxanthine, a step in the biosynthesis of menaquinone (MK, vitamin K2).
 
   
 0.844
ubiD
3-polyprenyl-4-hydroxybenzoate decarboxylase; Function of strongly homologous gene; enzyme; Belongs to the UbiD family.
 
   
 0.835
FRAAL1008
Putative aromatic acid decarboxylase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
   
 0.828
FRAAL1278
Putative Two-component system regulatory protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
   
    0.715
FRAAL1533
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
   
    0.715
FRAAL3925
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
  
    0.715
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.