Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FRAAL1122Alanine racemase; Catalyzes the interconversion of L-alanine and D-alanine. May also act on other amino acids; Belongs to the alanine racemase family. (387 aa)    
Predicted Functional Partners:
ddlA-2
D-alanine-D-alanine ligase A; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.984
murF
D-alanine:D-alanine-adding enzyme; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily.
   
 0.979
FRAAL1127
Putative ATPase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.962
ddlA
D-alanine--D-alanine ligase B; Cell wall formation; Belongs to the D-alanine--D-alanine ligase family.
 
 
 0.944
nnrD
Putative ribokinase; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of both epim [...]
 
    0.859
purQ
Phosphoribosylformylglycinamidine synthase I (FGAM synthase I); Part of the phosphoribosylformylglycinamidine synthase complex involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. The FGAM synthase complex is composed of three subunits. PurQ produces an ammonia molecule by converting glutamine to glutamate. PurL transfers the ammonia molecule to FGAR to form FGAM in an ATP- dependent manner. PurS interacts with PurQ and PurL and is t [...]
    
 0.837
gadB
Glutamate decarboxylase, PLP-dependent, isozyme beta; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the group II decarboxylase family.
    
  0.826
FRAAL0078
Putative aspartate aminotransferase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
    
 0.823
gdhA
Glutamate dehydrogenase (GDH); Function of strongly homologous gene; enzyme; Belongs to the Glu/Leu/Phe/Val dehydrogenases family.
    
 0.815
FRAAL0678
Glutamine synthetase (Glutamate--ammonia ligase); Function of strongly homologous gene; enzyme; Belongs to the glutamine synthetase family.
     
 0.814
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
Server load: low (40%) [HD]