STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hypF2Hydrogenase maturation protein hypF; Function of strongly homologous gene; enzyme. (824 aa)    
Predicted Functional Partners:
hypE2
Hydrogenase maturation protein; Function of strongly homologous gene; enzyme.
 
 
 0.981
hypD2
Hydrogenase expression/formation protein; Function of strongly homologous gene; enzyme.
 
  
 0.967
hypC2
Hydrogenase expression/formation protein hypC; Function of strongly homologous gene; molecular chaperone.
 
 
 0.967
hypE1
Hydrogenase maturation protein; Function of strongly homologous gene; enzyme.
 
 
 0.929
hypD1
Hydrogenase expression/formation protein; Function of strongly homologous gene; enzyme.
 
  
 0.861
hupL2
[NiFe] uptake hydrogenase, large subunit; Function of strongly homologous gene; enzyme.
 
 
 
 0.859
hypC1
Hydrogenase expression/formation protein; Function of strongly homologous gene; enzyme.
 
 
 0.857
FRAAL1826
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
       0.790
hypB2
Hydrogenase nickel incorporation protein; Function of strongly homologous gene; enzyme.
 
   
 0.755
hypA1
Hydrogenase nickel incorporation protein hypA; Involved in the maturation of [NiFe] hydrogenases. Required for nickel insertion into the metal center of the hydrogenase.
 
   
 0.723
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.