Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FRAAL1979Putative D-isomer specific 2-hydroxyacid dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (303 aa)    
Predicted Functional Partners:
serC
Phosphoserine aminotransferase (PSAT); Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily.
  
 
 0.648
FRAAL1980
Hypothetical protein; No homology to any previously reported sequences.
       0.555
FRAAL3674
Putative kinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
 
  0.524
FRAAL3259
Putative Sir2 family Transcriptional regulator; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; regulator.
 
 
  0.495
cysC
Adenosine 5'-phosphosulfate kinase (partial match); Function of strongly homologous gene; enzyme.
   
  
 0.494
FRAAL4224
Hypothetical protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
 0.484
gltB
Glutamate synthase, large subunit; Function of strongly homologous gene; enzyme.
  
 
 0.462
acuC
Acetoin dehydrogenase; Function of strongly homologous gene; enzyme.
   
 0.455
metH
B12-dependent homocysteine-N5-methyltetrahydrofolate transmethylase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
   
  
 0.444
hom
Homoserine dehydrogenase (HDH); Function of strongly homologous gene; enzyme.
  
 
 0.431
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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