Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
FRAAL2009Phosphate starvation-inducible protein PhoH and related proteins; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. (349 aa)    
Predicted Functional Partners:
ybeY
Conserved hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA.
 
  
 0.993
era
Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism.
 
  
 0.878
recO
DNA repair protein recO (Recombination protein O); Involved in DNA repair and RecF pathway recombination.
  
  
 0.838
FRAAL2011
Putative membrane protein containing CBS domain; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; transporter.
  
  
 0.823
FRAAL2012
Putative cytidine deaminase (Cytidine aminohydrolase) (CDA); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
  
  
 0.819
rsfS
Conserved hypothetical protein; Functions as a ribosomal silencing factor. Interacts with ribosomal protein L14 (rplN), blocking formation of intersubunit bridge B8. Prevents association of the 30S and 50S ribosomal subunits and the formation of functional ribosomes, thus repressing translation.
 
     0.693
cmk
Cytidylate kinase (CK) (Cytidine monophosphate kinase) (CMP kinase); Function of strongly homologous gene; enzyme.
 
    0.681
FRAAL5224
Conserved hypothetical protein; Homologs of previously reported genes of unknown function; Belongs to the class I-like SAM-binding methyltransferase superfamily. RsmB/NOP family.
 
    0.631
FRAAL2008
Conserved hypothetical protein; Specifically methylates the N3 position of the uracil ring of uridine 1498 (m3U1498) in 16S rRNA. Acts on the fully assembled 30S ribosomal subunit.
     
 0.629
ribA
Riboflavin biosynthesis protein ribA [Includes: GTP cyclohydrolase II; Catalyzes the conversion of D-ribulose 5-phosphate to formate and 3,4-dihydroxy-2-butanone 4-phosphate; In the C-terminal section; belongs to the GTP cyclohydrolase II family.
     
 0.593
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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