| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| FRAAL2009 | era | FRAAL2009 | FRAAL2013 | Phosphate starvation-inducible protein PhoH and related proteins; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.878 |
| FRAAL2009 | recO | FRAAL2009 | FRAAL2016 | Phosphate starvation-inducible protein PhoH and related proteins; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | DNA repair protein recO (Recombination protein O); Involved in DNA repair and RecF pathway recombination. | 0.838 |
| asd | def | FRAAL0604 | FRAAL0019 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of strongly homologous gene; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family. | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.713 |
| asd | gcvT | FRAAL0604 | FRAAL5148 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of strongly homologous gene; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family. | Aminomethyltransferase (Glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. | 0.672 |
| asd | purE | FRAAL0604 | FRAAL6664 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of strongly homologous gene; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.607 |
| asd | recO | FRAAL0604 | FRAAL2016 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of strongly homologous gene; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family. | DNA repair protein recO (Recombination protein O); Involved in DNA repair and RecF pathway recombination. | 0.727 |
| asd | trpD | FRAAL0604 | FRAAL5120 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of strongly homologous gene; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family. | Anthranilate phosphoribosyltransferase 1; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.677 |
| asd | tsaD | FRAAL0604 | FRAAL2797 | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of strongly homologous gene; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family. | Putative O-sialoglycoprotein endopeptidase, with actin-like ATPase domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.759 |
| def | asd | FRAAL0019 | FRAAL0604 | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Aspartate-semialdehyde dehydrogenase (ASA dehydrogenase) (ASADH); Function of strongly homologous gene; enzyme; Belongs to the aspartate-semialdehyde dehydrogenase family. | 0.713 |
| def | era | FRAAL0019 | FRAAL2013 | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | 0.484 |
| def | gcvT | FRAAL0019 | FRAAL5148 | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Aminomethyltransferase (Glycine cleavage system T protein); The glycine cleavage system catalyzes the degradation of glycine. | 0.698 |
| def | ispU | FRAAL0019 | FRAAL2017 | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Undecaprenyl pyrophosphate synthetase (di-trans, poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.438 |
| def | purE | FRAAL0019 | FRAAL6664 | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.730 |
| def | recO | FRAAL0019 | FRAAL2016 | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | DNA repair protein recO (Recombination protein O); Involved in DNA repair and RecF pathway recombination. | 0.780 |
| def | trpD | FRAAL0019 | FRAAL5120 | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Anthranilate phosphoribosyltransferase 1; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA). | 0.648 |
| def | tsaD | FRAAL0019 | FRAAL2797 | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | Putative O-sialoglycoprotein endopeptidase, with actin-like ATPase domain; Required for the formation of a threonylcarbamoyl group on adenosine at position 37 (t(6)A37) in tRNAs that read codons beginning with adenine. Is involved in the transfer of the threonylcarbamoyl moiety of threonylcarbamoyl-AMP (TC-AMP) to the N6 group of A37, together with TsaE and TsaB. TsaD likely plays a direct catalytic role in this reaction; Belongs to the KAE1 / TsaD family. | 0.841 |
| era | FRAAL2009 | FRAAL2013 | FRAAL2009 | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Phosphate starvation-inducible protein PhoH and related proteins; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology. | 0.878 |
| era | def | FRAAL2013 | FRAAL0019 | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Peptide deformylase 3 (PDF 3) (Polypeptide deformylase 3); Removes the formyl group from the N-terminal Met of newly synthesized proteins. Requires at least a dipeptide for an efficient rate of reaction. N-terminal L-methionine is a prerequisite for activity but the enzyme has broad specificity at other positions. | 0.484 |
| era | ispU | FRAAL2013 | FRAAL2017 | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Undecaprenyl pyrophosphate synthetase (di-trans, poly-cis-decaprenylcistransferase); Catalyzes the condensation of isopentenyl diphosphate (IPP) with allylic pyrophosphates generating different type of terpenoids. | 0.638 |
| era | purE | FRAAL2013 | FRAAL6664 | Putative GTP-binding protein; An essential GTPase that binds both GDP and GTP, with rapid nucleotide exchange. Plays a role in 16S rRNA processing and 30S ribosomal subunit biogenesis and possibly also in cell cycle regulation and energy metabolism. | Phosphoribosylaminoimidazole carboxylase = AIR carboxylase, catalytic subunit; Catalyzes the conversion of N5-carboxyaminoimidazole ribonucleotide (N5-CAIR) to 4-carboxy-5-aminoimidazole ribonucleotide (CAIR). | 0.474 |
