STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
valSValyl-tRNA synthetase; Catalyzes the attachment of valine to tRNA(Val). As ValRS can inadvertently accommodate and process structurally similar amino acids such as threonine, to avoid such errors, it has a 'posttransfer' editing activity that hydrolyzes mischarged Thr-tRNA(Val) in a tRNA- dependent manner. (906 aa)    
Predicted Functional Partners:
glyQS
Glycine--tRNA ligase alpha subunit; Function of strongly homologous gene; enzyme.
  
  
 0.955
guaA
GMP synthetase (glutamine aminotransferase); Catalyzes the synthesis of GMP from XMP.
  
  
 0.921
leuS
Leucyl-tRNA synthetase (Leucine--tRNA ligase); Function of strongly homologous gene; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
   
 
0.918
cysS1
Cysteinyl-tRNA synthetase (Cysteine--tRNA ligase) (CysS1); Function of strongly homologous gene; enzyme; Belongs to the class-I aminoacyl-tRNA synthetase family.
 
  
 0.909
gltX
Glutamyl-tRNA synthetase (Glutamate--tRNA ligase); Catalyzes the attachment of glutamate to tRNA(Glu) in a two- step reaction: glutamate is first activated by ATP to form Glu-AMP and then transferred to the acceptor end of tRNA(Glu).
 
 
 0.906
ileS
isoleucyl-tRNA synthetase; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 2 subfamily.
 
 
0.898
argS
Arginyl-tRNA synthetase (Arginine--tRNA ligase); Function of strongly homologous gene; enzyme.
  
  
 0.866
pheT
Phenylalanine tRNA synthetase, beta-subunit; Function of strongly homologous gene; enzyme; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily.
  
  
 0.845
thrS2
Threonyl-tRNA synthetase (Threonine--tRNA ligase); Function of strongly homologous gene; enzyme; Belongs to the class-II aminoacyl-tRNA synthetase family.
 
  
 0.844
hisS
Histidyl-tRNA synthetase (Histidine--tRNA ligase); Function of strongly homologous gene; enzyme.
 
 
 0.829
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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