Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
FRAAL2802Precorrin-6A synthase [deacetylating]; Function of strongly homologous gene; enzyme. (277 aa)    
Predicted Functional Partners:
cobK
Precorrin-6X reductase; Function of strongly homologous gene; enzyme.
 
 
 0.997
cobM
Precorrin-4 C11-methyltransferase (Precorrin-3 methylase); Function of strongly homologous gene; enzyme; Belongs to the precorrin methyltransferase family.
 
 
 0.989
cobE
Precorrin methylase (partial); Function of strongly homologous gene; enzyme.
  
  
 0.968
cobL
Precorrin-6Y C5,15-methyltransferase (decarboxylating); Function of strongly homologous gene; enzyme.
 
  
 0.959
cobH
Precorrin-8X methylmutase (Precorrin isomerase); Function of strongly homologous gene; enzyme.
 
  
 0.880
bioD
Dethiobiotin synthetase (Cobyric acid synthase); Catalyzes amidations at positions B, D, E, and G on adenosylcobyrinic A,C-diamide. NH(2) groups are provided by glutamine, and one molecule of ATP is hydrogenolyzed for each amidation. Belongs to the CobB/CobQ family. CobQ subfamily.
  
  
 0.833
cobI
Cobalamin biosynthesis protein COBIJ; Function of strongly homologous gene; enzyme.
 
  
 0.827
cobN
Cobalamin biosynthesis protein cobN; Function of strongly homologous gene; enzyme.
 
  
 0.701
FRAAL3733
Putative precorrin-8X methylmutase (cobH-like); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
  
 0.677
FRAAL2801
Hypothetical protein; No homology to any previously reported sequences.
       0.657
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
Server load: low (14%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.