STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
Experiments
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[Homology]
Score
FRAAL3244Putative ATP-dependent Clp protease; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme. (250 aa)    
Predicted Functional Partners:
clpS
ATP-dependent Clp protease adaptor protein clpS; Involved in the modulation of the specificity of the ClpAP- mediated ATP-dependent protein degradation; Belongs to the ClpS family.
  
 
 0.624
FRAAL0698
WD-repeat protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology.
  
 
 0.615
dnaK
Chaperone Hsp70 in DNA biosynthesis/cell division; Function of strongly homologous gene; molecular chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.615
FRAAL2972
Hypothetical protein; No homology to any previously reported sequences; Belongs to the heat shock protein 70 family.
  
 
 0.615
FRAAL3270
Putative Chaperone protein dnaK (Heat shock protein 70) (Heat shock 70 kDa protein) (HSP70); Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; molecular chaperone.
  
 
 0.615
FRAAL4947
Hypothetical protein; No homology to any previously reported sequences.
  
 
 0.615
FRAAL5750
Hypothetical protein; No homology to any previously reported sequences; Belongs to the heat shock protein 70 family.
  
 
 0.615
FRAAL5893
Hypothetical protein; No homology to any previously reported sequences; Belongs to the heat shock protein 70 family.
  
 
 0.615
dnaK-2
Chaperone Hsp70 in DNA biosynthesis/cell division; Acts as a chaperone; Belongs to the heat shock protein 70 family.
  
 
 0.615
grpE
Hsp 24 nucleotide exchange factor; Participates actively in the response to hyperosmotic and heat shock by preventing the aggregation of stress-denatured proteins, in association with DnaK and GrpE. It is the nucleotide exchange factor for DnaK and may function as a thermosensor. Unfolded proteins bind initially to DnaJ; upon interaction with the DnaJ-bound protein, DnaK hydrolyzes its bound ATP, resulting in the formation of a stable complex. GrpE releases ADP from DnaK; ATP binding to DnaK triggers the release of the substrate protein, thus completing the reaction cycle. Several roun [...]
  
 
 0.610
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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