STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
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Gene Fusion
Cooccurrence
Coexpression
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[Homology]
Score
FRAAL3294Putative Glutamate--cysteine ligase; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily. (383 aa)    
Predicted Functional Partners:
FRAAL1203
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; Belongs to the glutamate--cysteine ligase type 2 family. YbdK subfamily.
  
  
 
0.926
FRAAL4489
Conserved hypothetical protein; ATP-dependent carboxylate-amine ligase which exhibits weak glutamate--cysteine ligase activity; In the N-terminal section; belongs to the glutamate-- cysteine ligase type 2 family. YbdK subfamily.
 
  
 
0.907
FRAAL1606
Putative aminopeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
    
 0.905
FRAAL1858
Aminopeptidase N (Lysyl aminopeptidase) (Lys-AP) (Alanine aminopeptidase); Function of strongly homologous gene; enzyme.
    
 0.905
gshA
Glutamate--cysteine ligase GSHA (Gamma-glutamylcysteine synthetase) (Gamma-ECS) (GCS); Catalyzes the synthesis of gamma-glutamylcysteine (gamma-GC). This compound is used as substrate for the biosynthesis of the low- molecular thiol compound ergothioneine.
    
  0.902
pxpA
Putative lactam utilization protein; Catalyzes the cleavage of 5-oxoproline to form L-glutamate coupled to the hydrolysis of ATP to ADP and inorganic phosphate.
     
  0.900
pepA
Cytosol aminopeptidase (Leucine aminopeptidase) (LAP) (Leucyl aminopeptidase); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
pepA-2
Cytosol aminopeptidase (Leucine aminopeptidase) (LAP) (Leucyl aminopeptidase); Presumably involved in the processing and regular turnover of intracellular proteins. Catalyzes the removal of unsubstituted N- terminal amino acids from various peptides.
     
  0.900
FRAAL4547
Conserved hypothetical protein; Homologs of previously reported genes of unknown function.
      0.824
putA
Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial precursor (P5C dehydrogenase); Function of strongly homologous gene; enzyme; Belongs to the aldehyde dehydrogenase family.
   
 
  0.806
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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