STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
trpE-2Anthranilate synthase component I; Function of strongly homologous gene; enzyme. (445 aa)    
Predicted Functional Partners:
pabA
Aminodeoxychorismate synthase subunit II, component of p-aminobenzoate synthase multienzyme complex; Function of strongly homologous gene; enzyme.
 0.999
FRAAL4648
(2,3-dihydroxybenzoyl)adenylate synthase (2, 3-dihydroxybenzoate-AMP ligase; Function of strongly homologous gene; enzyme.
 
 
 0.998
trpD
Anthranilate phosphoribosyltransferase 1; Catalyzes the transfer of the phosphoribosyl group of 5- phosphorylribose-1-pyrophosphate (PRPP) to anthranilate to yield N-(5'- phosphoribosyl)-anthranilate (PRA).
 0.997
FRAAL3440
Putative Anthranilate synthase, phenazine specific [Includes: Glutamine amidotransferase]; Function proposed based on presence of conserved amino acid motif, structural feature or limited homology; enzyme.
 
0.994
mbtA
2,3-dihydroxybenzoate-AMP ligase; Function of strongly homologous gene; enzyme.
 
 
 0.993
FRAAL2557
Non-ribosomal peptide synthetase (Fragment); Function of strongly homologous gene; enzyme.
  
  
 0.988
FRAAL2542
Non-ribosomal peptide synthetase; Function of strongly homologous gene; enzyme; Belongs to the ATP-dependent AMP-binding enzyme family.
 
  
 0.987
trpC
Indole-3-glycerol phosphate synthase 1 (IGPS 1); Function of strongly homologous gene; enzyme; Belongs to the TrpC family.
 
 0.986
aroF-2
Chorismate synthase (5-enolpyruvylshikimate-3-phosphate phospholyase); Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system.
 
 
 0.978
FRAAL4647
Hypothetical protein, putative Phosphopantetheine-binding domain; No homology to any previously reported sequences.
 
  
 0.974
Your Current Organism:
Frankia alni
NCBI taxonomy Id: 326424
Other names: F. alni ACN14a, Frankia alni ACN14a, Frankia alni str. ACN14a, Frankia alni strain ACN14a, Frankia sp. ACN14a
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