Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cagg_0002Peptidase S41; PFAM: PDZ/DHR/GLGF domain protein; peptidase S41; KEGG: cau:Caur_2531 peptidase S41. (465 aa)    
Predicted Functional Partners:
Cagg_0534
PFAM: peptidase M50; SMART: PDZ/DHR/GLGF domain protein; KEGG: cau:Caur_3574 peptidase M50.
 
  
 0.707
Cagg_2402
MCP methyltransferase, CheR-type with Tpr repeats; KEGG: cau:Caur_1670 protein-glutamate O-methyltransferase; PFAM: MCP methyltransferase CheR-type; TPR repeat-containing protein; Tetratricopeptide TPR_2 repeat protein; SMART: Tetratricopeptide domain protein.
  
 
 0.638
Cagg_2636
PFAM: 4Fe-4S ferredoxin iron-sulfur binding domain protein; pyruvate ferredoxin/flavodoxin oxidoreductase; pyruvate flavodoxin/ferredoxin oxidoreductase domain protein; 4Fe-4S ferredoxin, iron-sulphur binding, conserved site; KEGG: cau:Caur_2080 pyruvate flavodoxin/ferredoxin oxidoreductase domain-containing protein.
   
 
 0.555
Cagg_0003
Putative transcriptional regulator, GntR family; PFAM: aminotransferase class I and II; KEGG: cau:Caur_2532 aminotransferase class I and II.
       0.537
Cagg_0004
PFAM: pseudouridine synthase; KEGG: cau:Caur_2533 pseudouridine synthase.
       0.537
Cagg_2338
Tetratricopeptide TPR_4; PFAM: TPR repeat-containing protein; Tetratricopeptide TPR_4; SMART: Tetratricopeptide domain protein; KEGG: cau:Caur_1578 TPR repeat-containing protein.
 
 
 0.488
Cagg_0949
PFAM: UBA/THIF-type NAD/FAD binding protein; Rhodanese domain protein; MoeZ/MoeB domain protein; KEGG: cau:Caur_3492 UBA/ThiF-type NAD/FAD binding protein.
  
    0.466
Your Current Organism:
Chloroflexus aggregans
NCBI taxonomy Id: 326427
Other names: C. aggregans DSM 9485, Chloroflexus aggregans DSM 9485, Chloroflexus aggregans MD-66, Chloroflexus aggregans str. DSM 9485, Chloroflexus aggregans strain DSM 9485
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