STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cagg_0664PFAM: Thioredoxin domain; KEGG: cau:Caur_0205 thioredoxin domain-containing protein. (282 aa)    
Predicted Functional Partners:
Cagg_3576
TIGRFAM: YD repeat protein; PFAM: cell wall hydrolase/autolysin; YD repeat-containing protein; KEGG: mba:Mbar_A3399 hypothetical protein.
   
   0.766
Cagg_2767
Ribonucleoside-diphosphate reductase, adenosylcobalamin-dependent; Catalyzes the reduction of ribonucleotides to deoxyribonucleotides. May function to provide a pool of deoxyribonucleotide precursors for DNA repair during oxygen limitation and/or for immediate growth after restoration of oxygen.
  
 
 0.757
Cagg_2685
TIGRFAM: thioredoxin reductase; PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; HI0933 family protein; FAD dependent oxidoreductase; KEGG: cau:Caur_2066 thioredoxin reductase.
 
 
 0.741
groL
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.729
groL-2
Chaperonin GroEL; Prevents misfolding and promotes the refolding and proper assembly of unfolded polypeptides generated under stress conditions.
   
 
 0.729
Cagg_0128
PFAM: FAD-dependent pyridine nucleotide-disulphide oxidoreductase; KEGG: cau:Caur_0222 FAD-dependent pyridine nucleotide-disulphide oxidoreductase.
  
 
 0.700
Cagg_0491
KEGG: cau:Caur_3586 putative secreted protein.
  
 
 0.700
Cagg_0665
TIGRFAM: LPPG domain protein containing protein; PFAM: protein of unknown function UPF0052 and CofD; KEGG: cau:Caur_0204 LPPG:FO 2-phospho-L-lactate transferase.
       0.621
Cagg_0145
PFAM: glutamine amidotransferase class-II; glutamate synthase alpha subunit domain protein; ferredoxin-dependent glutamate synthase; glutamate synthase; KEGG: cau:Caur_3258 glutamate synthase (ferredoxin).
   
 
 0.568
Cagg_0663
KEGG: cau:Caur_0206 hypothetical protein.
       0.562
Your Current Organism:
Chloroflexus aggregans
NCBI taxonomy Id: 326427
Other names: C. aggregans DSM 9485, Chloroflexus aggregans DSM 9485, Chloroflexus aggregans MD-66, Chloroflexus aggregans str. DSM 9485, Chloroflexus aggregans strain DSM 9485
Server load: low (40%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.