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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
Cagg_1908Adenylate/guanylate cyclase with GAF sensor and FHA domain; PFAM: Forkhead-associated protein; adenylyl cyclase class-3/4/guanylyl cyclase; GAF domain protein; KEGG: cau:Caur_1127 adenylyl cyclase class-3/4/guanylyl cyclase. (518 aa)    
Predicted Functional Partners:
Cagg_3222
PFAM: protein of unknown function RIO1; tyrosine protein kinase; PASTA domain containing protein; Serine/threonine protein kinase-related; SMART: serine/threonine protein kinase; KEGG: cau:Caur_0486 protein kinase.
 
 
 0.946
Cagg_2958
PFAM: adenylyl cyclase class-3/4/guanylyl cyclase; KEGG: cau:Caur_3520 adenylyl cyclase class-3/4/guanylyl cyclase.
 
 
 
0.934
ndk
Nucleoside-diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
    
 0.914
Cagg_0312
KEGG: cau:Caur_3128 pyruvate kinase; TIGRFAM: pyruvate kinase; PFAM: HpcH/HpaI aldolase; Pyruvate kinase barrel; Pyruvate kinase alpha/beta; Belongs to the pyruvate kinase family.
   
 0.907
Cagg_0858
PFAM: metal-dependent phosphohydrolase HD sub domain; KEGG: cau:Caur_3093 metal-dependent phosphohydrolase.
    
 0.903
Cagg_2530
(p)ppGpp synthetase I, SpoT/RelA; In eubacteria ppGpp (guanosine 3'-diphosphate 5-' diphosphate) is a mediator of the stringent response that coordinates a variety of cellular activities in response to changes in nutritional abundance.
    
 0.903
Cagg_0839
PAS/PAC sensor hybrid histidine kinase; KEGG: cau:Caur_3796 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
 
 0.883
Cagg_0067
Serine/threonine protein kinase with WD40 repeats; PFAM: tyrosine protein kinase; WD-40 repeat protein; aminoglycoside phosphotransferase; SMART: serine/threonine protein kinase; KEGG: cau:Caur_3288 WD-40 repeat-containing protein.
 
 
 
 0.865
Cagg_2419
PFAM: cyclic nucleotide-binding; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: cau:Caur_1013 stage II sporulation E family protein.
 0.858
Cagg_3042
PFAM: WD-40 repeat protein; SMART: serine/threonine protein kinase; KEGG: cau:Caur_2351 WD-40 repeat-containing protein.
 
 
 
 0.844
Your Current Organism:
Chloroflexus aggregans
NCBI taxonomy Id: 326427
Other names: C. aggregans DSM 9485, Chloroflexus aggregans DSM 9485, Chloroflexus aggregans MD-66, Chloroflexus aggregans str. DSM 9485, Chloroflexus aggregans strain DSM 9485
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