Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
Cagg_2007Phosphoenolpyruvate-protein phosphotransferase; General (non sugar-specific) component of the phosphoenolpyruvate-dependent sugar phosphotransferase system (sugar PTS). This major carbohydrate active-transport system catalyzes the phosphorylation of incoming sugar substrates concomitantly with their translocation across the cell membrane. Enzyme I transfers the phosphoryl group from phosphoenolpyruvate (PEP) to the phosphoryl carrier protein (HPr). (556 aa)    
Predicted Functional Partners:
Cagg_2006
TIGRFAM: phosphocarrier, HPr family; PFAM: phosphoryl transfer system HPr; KEGG: cau:Caur_1321 HPr family phosphocarrier protein.
 
 0.998
Cagg_2895
TIGRFAM: phosphocarrier, HPr family; phosphoenolpyruvate-protein phosphotransferase; PFAM: PEP-utilizing protein; phosphoenolpyruvate-dependent sugar phosphotransferase system EIIA 2; phosphoryl transfer system HPr; PEP-utilising protein mobile region; PEP-utilising protein domain protein; KEGG: cau:Caur_0801 phosphoenolpyruvate-protein phosphotransferase.
 
0.992
Cagg_2897
TIGRFAM: PTS system, fructose-specific, IIB subunnit; PTS system, fructose subfamily, IIC subunit; PFAM: phosphotransferase system EIIC; phosphotransferase system PTS fructose-specific IIB subunit; KEGG: cau:Caur_0803 PTS system, fructose subfamily, IIC subunit.
 
 
 0.992
Cagg_2004
TIGRFAM: dihydroxyacetone kinase, L subunit; PFAM: Dak phosphatase; KEGG: cau:Caur_1319 dihydroxyacetone kinase, L subunit.
 
  
 0.851
Cagg_2005
TIGRFAM: dihydroxyacetone kinase, phosphotransfer subunit; PFAM: PTS system fructose subfamily IIA component; KEGG: cau:Caur_1320 dihydroxyacetone kinase, phosphotransfer subunit.
 
   
 0.849
Cagg_2896
KEGG: cau:Caur_0802 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.716
Cagg_0744
KEGG: cau:Caur_2662 1-phosphofructokinase; TIGRFAM: 1-phosphofructokinase; PFAM: PfkB domain protein; Belongs to the carbohydrate kinase PfkB family.
 
  
 0.665
eno
Phosphopyruvate hydratase; Catalyzes the reversible conversion of 2-phosphoglycerate into phosphoenolpyruvate. It is essential for the degradation of carbohydrates via glycolysis; Belongs to the enolase family.
 
  
 0.486
Cagg_2054
Two component transcriptional regulator, AraC family; PFAM: helix-turn-helix- domain containing protein AraC type; periplasmic binding protein/LacI transcriptional regulator; response regulator receiver; ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: cau:Caur_0894 ATPase domain-containing protein.
   
 
 0.468
pgi
PFAM: phosphoglucose isomerase (PGI); KEGG: cau:Caur_2179 glucose-6-phosphate isomerase; Belongs to the GPI family.
  
  
 0.424
Your Current Organism:
Chloroflexus aggregans
NCBI taxonomy Id: 326427
Other names: C. aggregans DSM 9485, Chloroflexus aggregans DSM 9485, Chloroflexus aggregans MD-66, Chloroflexus aggregans str. DSM 9485, Chloroflexus aggregans strain DSM 9485
Server load: medium (44%) [HD]