Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cagg_2008PFAM: Na-Ca exchanger/integrin-beta4; KEGG: cau:Caur_1388 Na-Ca exchanger/integrin-beta4. (3168 aa)    
Predicted Functional Partners:
Cagg_1738
TIGRFAM: conserved repeat domain protein; PFAM: protein of unknown function DUF11; KEGG: cau:Caur_0912 hypothetical protein.
 
 
 0.941
Cagg_1770
KEGG: cau:Caur_1398 peptidase domain-containing protein.
 
 
 0.941
Cagg_3153
KEGG: cau:Caur_0391 hypothetical protein.
 
 
 0.941
Cagg_2072
KEGG: cau:Caur_1477 hypothetical protein.
 
 
 0.940
Cagg_3634
KEGG: cau:Caur_0267 polymorphic outer membrane protein.
 
 
 0.937
Cagg_1880
TIGRFAM: conserved repeat domain protein; PFAM: protein of unknown function DUF11; KEGG: cau:Caur_1090 hypothetical protein.
 
 
 0.888
Cagg_2179
TIGRFAM: LPXTG-motif cell wall anchor domain protein; KEGG: cau:Caur_1201 cell wall anchor domain-containing protein.
 
 
 0.879
Cagg_1457
KEGG: cau:Caur_1711 hypothetical protein.
 
    0.876
Cagg_2009
PAS/PAC sensor signal transduction histidine kinase; KEGG: cau:Caur_1387 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein.
 
   
 0.864
Cagg_1408
PFAM: Peptidoglycan-binding domain 1 protein; KEGG: cau:Caur_0781 peptidoglycan binding domain-containing protein.
 
  
 0.847
Your Current Organism:
Chloroflexus aggregans
NCBI taxonomy Id: 326427
Other names: C. aggregans DSM 9485, Chloroflexus aggregans DSM 9485, Chloroflexus aggregans MD-66, Chloroflexus aggregans str. DSM 9485, Chloroflexus aggregans strain DSM 9485
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