STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Coexpression
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[Homology]
Score
Cagg_2467PFAM: response regulator receiver; Stage II sporulation E family protein; SMART: protein phosphatase 2C domain protein; KEGG: syn:slr1983 two-component response regulator. (385 aa)    
Predicted Functional Partners:
Cagg_2555
Anti-sigma-factor antagonist; TIGRFAM: anti-anti-sigma factor; PFAM: Sulfate transporter/antisigma-factor antagonist STAS; KEGG: cau:Caur_1060 anti-anti-sigma factor; Belongs to the anti-sigma-factor antagonist family.
 
 
 0.923
Cagg_0785
Diguanylate cyclase with GAF sensor; TIGRFAM: diguanylate cyclase; PFAM: GGDEF domain containing protein; GAF domain protein; KEGG: cau:Caur_3514 diguanylate cyclase.
  
 0.877
Cagg_0968
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: cau:Caur_3473 ATPase domain-containing protein.
 
    0.786
Cagg_2189
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; KEGG: cau:Caur_1267 histidine kinase.
 
    0.767
Cagg_2746
PAS/PAC sensor signal transduction histidine kinase; KEGG: cau:Caur_0804 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; SMART: PAS domain containing protein.
  
    0.766
Cagg_0496
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: cau:Caur_3589 histidine kinase.
 
     0.762
Cagg_0553
Response regulator receiver modulated diguanylate cyclase/phosphodiesterase with PAS/PAC sensor(s); KEGG: cau:Caur_3534 diguanylate cyclase; TIGRFAM: PAS sensor protein; diguanylate cyclase; PFAM: GGDEF domain containing protein; EAL domain protein; response regulator receiver; PAS fold-3 domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
  
  
 0.756
Cagg_0555
PAS/PAC sensor signal transduction histidine kinase; KEGG: cau:Caur_3536 PAS sensor protein; TIGRFAM: PAS sensor protein; PFAM: ATP-binding region ATPase domain protein; histidine kinase A domain protein; PAS fold-4 domain protein; PAS fold domain protein; SMART: PAS domain containing protein; PAC repeat-containing protein.
 
     0.751
Cagg_0838
PFAM: GAF domain protein; ATP-binding region ATPase domain protein; histidine kinase A domain protein; SMART: histidine kinase HAMP region domain protein; KEGG: aeh:Mlg_1802 GAF sensor signal transduction histidine kinase.
 
     0.743
Cagg_3303
Histidine kinase; PFAM: ATP-binding region ATPase domain protein; histidine kinase HAMP region domain protein; histidine kinase A domain protein; KEGG: cau:Caur_2433 histidine kinase.
   
 0.723
Your Current Organism:
Chloroflexus aggregans
NCBI taxonomy Id: 326427
Other names: C. aggregans DSM 9485, Chloroflexus aggregans DSM 9485, Chloroflexus aggregans MD-66, Chloroflexus aggregans str. DSM 9485, Chloroflexus aggregans strain DSM 9485
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