Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
Cagg_3045PFAM: oxidoreductase molybdopterin binding; KEGG: cau:Caur_2348 oxidoreductase molybdopterin binding. (202 aa)    
Predicted Functional Partners:
msrQ
Ferric reductase domain protein protein transmembrane component domain protein; Part of the MsrPQ system that repairs oxidized cell envelope proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated cell envelope proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic su [...]
  
  
 0.821
nfi
Deoxyribonuclease V; DNA repair enzyme involved in the repair of deaminated bases. Selectively cleaves double-stranded DNA at the second phosphodiester bond 3' to a deoxyinosine leaving behind the intact lesion on the nicked DNA.
       0.821
Cagg_1452
PFAM: oxidoreductase molybdopterin binding; KEGG: cau:Caur_2488 oxidoreductase molybdopterin binding.
  
     0.665
Cagg_3530
KEGG: cau:Caur_3002 hypothetical protein.
   
 
 0.631
Cagg_3043
Sterol 3-beta-glucosyltransferase; PFAM: glycosyl transferase family 28; KEGG: cau:Caur_2350 glycosyl transferase family protein.
 
     0.599
Cagg_3044
PFAM: Rieske [2Fe-2S] domain protein; KEGG: cau:Caur_2349 Rieske (2Fe-2S) domain-containing protein.
     
 0.558
Cagg_1522
Cytochrome c oxidase, subunit II; Subunits I and II form the functional core of the enzyme complex. Electrons originating in cytochrome c are transferred via heme a and Cu(A) to the binuclear center formed by heme a3 and Cu(B).
  
 
 0.456
Cagg_1526
KEGG: cau:Caur_2137 hypothetical protein.
   
 
 0.456
Cagg_3383
KEGG: cau:Caur_0625 hypothetical protein.
   
 
 0.456
Cagg_3384
KEGG: cau:Caur_0624 transmembrane prediction.
   
 
 0.456
Your Current Organism:
Chloroflexus aggregans
NCBI taxonomy Id: 326427
Other names: C. aggregans DSM 9485, Chloroflexus aggregans DSM 9485, Chloroflexus aggregans MD-66, Chloroflexus aggregans str. DSM 9485, Chloroflexus aggregans strain DSM 9485
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