Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
folXD-erythro-7,8-dihydroneopterin aldolase; Function of strongly homologous gene; enzyme. (118 aa)    
Predicted Functional Partners:
folE
GTP cyclohydrolase I; Function of strongly homologous gene; enzyme.
  
 
 0.998
folM
Putative alternative dihydrofolate reductase, NAD(P)-binding domain; Function of strongly homologous gene; enzyme.
 
   
 0.927
folE2
Conserved protein of unknown function; Converts GTP to 7,8-dihydroneopterin triphosphate.
    
 0.905
phoD
Putative alkaline phosphatase D (APaseD); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
     
 0.902
PSHAa2976
Alkaline phosphatase; Function of strongly homologous gene; enzyme; Belongs to the alkaline phosphatase family.
     
  0.900
PSHAa2977
Secreted alkaline phosphatase; Function of strongly homologous gene; enzyme; Belongs to the alkaline phosphatase family.
     
  0.900
PSHAb0500
Putative alkaline phosphatase; Function of strongly homologous gene; enzyme; Belongs to the alkaline phosphatase family.
     
  0.900
PSHAa2301
Putative phosphokinase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
 
 
 0.878
folP
Dihydropteroate synthase (DHPS) (Dihydropteroate pyrophosphorylase); Catalyzes the condensation of para-aminobenzoate (pABA) with 6-hydroxymethyl-7,8-dihydropterin diphosphate (DHPt-PP) to form 7,8- dihydropteroate (H2Pte), the immediate precursor of folate derivatives.
  
  
 0.851
folK
2-amino-4-hydroxy-6-hydroxymethyldihyropteridine pyrophosphokinase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.828
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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