STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
nadENAD synthetase; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses ammonia as a nitrogen source. (278 aa)    
Predicted Functional Partners:
nadD
Nicotinic acid mononucleotide adenylyltransferase, NAD(P)-requiring; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
  
 
 0.932
nadK
NAD kinase; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
    
 0.930
PSHAb0168
Putative sirtuin; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
    
 0.926
PSHAa0076
Conserved protein of unknown function similar to YceH of E. coli; Homologs of previously reported genes of unknown function; Belongs to the UPF0502 family.
      0.925
PSHAa1926
Putative NTP pyrophosphatase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme; Belongs to the Nudix hydrolase family.
  
 
 0.906
sthA
Soluble pyridine nucleotide transhydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
    
 0.901
mazG
Nucleoside triphosphate pyrophosphohydrolase, non-specific; Function of strongly homologous gene; enzyme.
     
  0.900
kdsA
3-deoxy-D-manno-octulosonic acid 8-P synthetase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the KdsA family.
      0.856
rnt
RNase T, degrades tRNA, has exonuclease and ssDNAse activity; Trims short 3' overhangs of a variety of RNA species, leaving a one or two nucleotide 3' overhang. Responsible for the end-turnover of tRNA: specifically removes the terminal AMP residue from uncharged tRNA (tRNA-C-C-A). Also appears to be involved in tRNA biosynthesis.
      0.690
smvA
Putative SmvA (YddG) efflux protein; Function of strongly homologous gene; transporter.
      0.646
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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