Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
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[Homology]
Score
cyaYPutative CyaY, involved in iron scavenging and/or transfer to heme; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis. (107 aa)    
Predicted Functional Partners:
iscU
Fe-S assembly protein; A scaffold on which IscS assembles Fe-S clusters. It is likely that Fe-S cluster coordination is flexible as the role of this complex is to build and then hand off Fe-S clusters.
  
 
 0.955
PSHAa0096
Putative phospholipase/carboxylesterase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
  
 0.872
fdx
[2Fe-2S] ferredoxin, electron carrier protein, involved in assembly of Fe-S clusters; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 
 0.872
hscB
Co-chaperone protein Hsc20, involved in assembly of Fe-S clusters (specific for IscU); Co-chaperone involved in the maturation of iron-sulfur cluster-containing proteins. Seems to help targeting proteins to be folded toward HscA; Belongs to the HscB family.
  
 
 0.866
PSHAa0097
Homologs of previously reported genes of unknown function.
       0.836
hscA
Chaperone protein HscA homolog; Chaperone involved in the maturation of iron-sulfur cluster- containing proteins. Has a low intrinsic ATPase activity which is markedly stimulated by HscB.
  
 0.819
hemH
Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
    
 
 0.801
hemC
Hydroxymethylbilane synthase (porphobilinogen deaminase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.787
hemDX
uroporphyrinogen-III synthase HemD (N terminal)/Uroporphyrin-III C-methyltransferase (C terminal); Function of strongly homologous gene; enzyme.
       0.787
hemY
Putative HemY (Uncharacterized enzyme of heme biosynthesis); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
       0.787
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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