Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
PSHAa0096Putative phospholipase/carboxylesterase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. (223 aa)    
Predicted Functional Partners:
cyaY
Putative CyaY, involved in iron scavenging and/or transfer to heme; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
  
  
 0.872
PSHAa0097
Homologs of previously reported genes of unknown function.
       0.836
hemC
Hydroxymethylbilane synthase (porphobilinogen deaminase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
       0.787
hemDX
uroporphyrinogen-III synthase HemD (N terminal)/Uroporphyrin-III C-methyltransferase (C terminal); Function of strongly homologous gene; enzyme.
  
    0.787
hemY
Putative HemY (Uncharacterized enzyme of heme biosynthesis); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
       0.787
lysA
Putative diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.711
PSHAa1344
Homologs of previously reported genes of unknown function.
     
 0.577
cysJ
Sulfite reductase, alpha subunit (flavoprotein); Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. The flavoprotein component catalyzes the electron flow from NADPH -> FAD -> FMN to the hemoprotein component.
     
  0.567
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Adenosine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
       0.551
PSHAa0094
Putative small periplasmic lipoprotein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; structural protein.
       0.525
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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