STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
hemYPutative HemY (Uncharacterized enzyme of heme biosynthesis); Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy. (368 aa)    
Predicted Functional Partners:
hemDX
uroporphyrinogen-III synthase HemD (N terminal)/Uroporphyrin-III C-methyltransferase (C terminal); Function of strongly homologous gene; enzyme.
 
  
 0.959
hemC
Hydroxymethylbilane synthase (porphobilinogen deaminase); Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.904
PSHAa0097
Homologs of previously reported genes of unknown function.
  
    0.814
cyaY
Putative CyaY, involved in iron scavenging and/or transfer to heme; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
       0.787
PSHAa0096
Putative phospholipase/carboxylesterase family protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
       0.787
add
Adenosine deaminase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the metallo-dependent hydrolases superfamily. Adenosine and AMP deaminases family. Adenosine deaminase subfamily.
 
     0.746
PSHAa0091
Conserved protein of unknown function conserved in bacteria; Homologs of previously reported genes of unknown function.
 
    0.679
PSHAa0101
Putative sensor protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; receptor.
       0.663
lysA
Putative diaminopimelate decarboxylase; Specifically catalyzes the decarboxylation of meso- diaminopimelate (meso-DAP) to L-lysine.
       0.609
syd
Syd protein; Interacts with the SecY protein in vivo. May bind preferentially to an uncomplexed state of SecY, thus functioning either as a chelating agent for excess SecY in the cell or as a regulatory factor that negatively controls the translocase function. Belongs to the Syd family.
  
     0.586
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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