Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
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[Homology]
Score
PSHAa0125Homologs of previously reported genes of unknown function. (207 aa)    
Predicted Functional Partners:
PSHAa1826
Putative sigma factor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; factor; Belongs to the sigma-70 factor family. ECF subfamily.
  
    0.618
PSHAa0505
Homologs of previously reported genes of unknown function.
  
     0.612
PSHAa1330
Putative D-alanyl-D-alanine carboxypeptidase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme.
  
     0.611
PSHAa2459
Putative membrane protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; membrane component.
  
     0.580
thyA
Thymidylate synthetase; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis.
    
 0.546
pyrB
Aspartate transcarbamoylase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aspartate/ornithine carbamoyltransferase superfamily.
  
     0.532
PSHAa0124
Conserved protein of unknown function (similar to E. coli YacL); Homologs of previously reported genes of unknown function.
       0.521
PSHAa2962
Homologs of previously reported genes of unknown function.
  
     0.513
ndk
Nucleoside diphosphate kinase; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family.
     
  0.500
PSHAa1825
Putative transmembrane sensor; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy.
  
     0.453
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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