Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
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empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
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from curated databases
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Assay-based Predictions
experimentally determined
co-expression
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gene neighborhood
gene co-occurrence
gene fusions
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[Homology]
Score
acnAAconitate hydratase (likely to be used in stationary phase); Catalyzes the isomerization of citrate to isocitrate via cis- aconitate. (914 aa)    
Predicted Functional Partners:
icd
Isocitrate dehydrogenase, specific for NADP+; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
 
 0.988
prpC
Methylcitrate synthase (citrate synthase 2); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
 
 0.988
gltA
Citrate synthase; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the citrate synthase family.
 
 0.985
PSHAa1772
Homologs of previously reported genes of unknown function.
  
 
 0.973
PSHAb0465
Probable isopropylmalate dehydrogenase; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
  
 0.951
acnB
Bifunctional protein [Includes: aconitate hydratase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the aconitase/IPM isomerase family.
    
 0.950
prpB
2-methylisocitrate lyase; Catalyzes the thermodynamically favored C-C bond cleavage of (2R,3S)-2-methylisocitrate to yield pyruvate and succinate. Belongs to the isocitrate lyase/PEP mutase superfamily. Methylisocitrate lyase family.
  
 0.941
PSHAa1727
Isocitrate dehydrogenase; Function of strongly homologous gene; enzyme; Belongs to the monomeric-type IDH family.
 
 
 0.923
aceA
Isocitrate lyase 2; Function of homologous gene experimentally demonstrated in an other organism; enzyme.
   
 
 0.923
prpD
2-methyl citrate dehydratase; Function of strongly homologous gene; enzyme.
  
 
 0.922
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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