| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| PSHAa1004 | cysG | PSHAa1004 | PSHAa0213 | Putative NADH dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.591 |
| PSHAa1004 | snaA | PSHAa1004 | PSHAa0210 | Putative NADH dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Putative sodium/sulfate symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | 0.443 |
| cysC | cysD | PSHAa0209 | PSHAa0212 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.999 |
| cysC | cysG | PSHAa0209 | PSHAa0213 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.982 |
| cysC | cysN | PSHAa0209 | PSHAa0211 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| cysC | cysQ | PSHAa0209 | PSHAa0208 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Likely to be PAP (3',5' adenosine diphosphate) 3' phosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.996 |
| cysC | snaA | PSHAa0209 | PSHAa0210 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Putative sodium/sulfate symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | 0.896 |
| cysD | cysC | PSHAa0212 | PSHAa0209 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.999 |
| cysD | cysG | PSHAa0212 | PSHAa0213 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.977 |
| cysD | cysN | PSHAa0212 | PSHAa0211 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
| cysD | cysQ | PSHAa0212 | PSHAa0208 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Likely to be PAP (3',5' adenosine diphosphate) 3' phosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.982 |
| cysD | snaA | PSHAa0212 | PSHAa0210 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Putative sodium/sulfate symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | 0.837 |
| cysG | PSHAa1004 | PSHAa0213 | PSHAa1004 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative NADH dehydrogenase; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.591 |
| cysG | cysC | PSHAa0213 | PSHAa0209 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.982 |
| cysG | cysD | PSHAa0213 | PSHAa0212 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.977 |
| cysG | cysN | PSHAa0213 | PSHAa0211 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.924 |
| cysG | cysQ | PSHAa0213 | PSHAa0208 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Likely to be PAP (3',5' adenosine diphosphate) 3' phosphatase; Converts adenosine-3',5'-bisphosphate (PAP) to AMP. Belongs to the inositol monophosphatase superfamily. CysQ family. | 0.768 |
| cysG | snaA | PSHAa0213 | PSHAa0210 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative sodium/sulfate symporter; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; transporter. | 0.784 |
| cysN | cysC | PSHAa0211 | PSHAa0209 | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.999 |
| cysN | cysD | PSHAa0211 | PSHAa0212 | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.999 |