node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
PSHAb0097 | cysC | PSHAb0097 | PSHAa0209 | Putative enzyme protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.869 |
PSHAb0097 | cysG | PSHAb0097 | PSHAa0213 | Putative enzyme protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.905 |
PSHAb0097 | cysI | PSHAb0097 | PSHAa0155 | Putative enzyme protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.708 |
PSHAb0097 | cysN | PSHAb0097 | PSHAa0211 | Putative enzyme protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.910 |
cysC | PSHAb0097 | PSHAa0209 | PSHAb0097 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Putative enzyme protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.869 |
cysC | cysD | PSHAa0209 | PSHAa0212 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.999 |
cysC | cysG | PSHAa0209 | PSHAa0213 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.989 |
cysC | cysH | PSHAa0209 | PSHAa0156 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 3'-phosphoadenosine 5'-phosphosulfate (PAPS) reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.999 |
cysC | cysI | PSHAa0209 | PSHAa0155 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.946 |
cysC | cysN | PSHAa0209 | PSHAa0211 | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
cysD | cysC | PSHAa0212 | PSHAa0209 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.999 |
cysD | cysG | PSHAa0212 | PSHAa0213 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 0.983 |
cysD | cysH | PSHAa0212 | PSHAa0156 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 3'-phosphoadenosine 5'-phosphosulfate (PAPS) reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.909 |
cysD | cysI | PSHAa0212 | PSHAa0155 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.892 |
cysD | cysN | PSHAa0212 | PSHAa0211 | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | ATP-sulfurylase, subunit 1 (ATP:sulfate adenylyltransferase); May be the GTPase, regulating ATP sulfurylase activity. Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. CysN/NodQ subfamily. | 0.999 |
cysG | PSHAb0097 | PSHAa0213 | PSHAb0097 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Putative enzyme protein; Function proposed based on presence of conserved amino acid motif, structural feature or limited homolgy; enzyme. | 0.905 |
cysG | cysC | PSHAa0213 | PSHAa0209 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Adenosine 5'-phosphosulfate kinase; Catalyzes the synthesis of activated sulfate. | 0.989 |
cysG | cysD | PSHAa0213 | PSHAa0212 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | ATP-sulfurylase, subunit 2 (ATP:sulfate adenylyltransferase); Function of homologous gene experimentally demonstrated in an other organism; enzyme. | 0.983 |
cysG | cysH | PSHAa0213 | PSHAa0156 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | 3'-phosphoadenosine 5'-phosphosulfate (PAPS) reductase; Reduction of activated sulfate into sulfite. Belongs to the PAPS reductase family. CysH subfamily. | 0.966 |
cysG | cysI | PSHAa0213 | PSHAa0155 | Multifunctional siroheme synthase: uroporphyrinogen methyltransferase; Multifunctional enzyme that catalyzes the SAM-dependent methylations of uroporphyrinogen III at position C-2 and C-7 to form precorrin-2 via precorrin-1. Then it catalyzes the NAD-dependent ring dehydrogenation of precorrin-2 to yield sirohydrochlorin. Finally, it catalyzes the ferrochelation of sirohydrochlorin to yield siroheme. | Sulfite reductase, beta subunit, NADPH-dependent hemoprotein; Component of the sulfite reductase complex that catalyzes the 6-electron reduction of sulfite to sulfide. This is one of several activities required for the biosynthesis of L-cysteine from sulfate. Belongs to the nitrite and sulfite reductase 4Fe-4S domain family. | 0.989 |