STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
dsbAPeriplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme. (207 aa)    
Predicted Functional Partners:
porA
Periplasmic protein, disulfide bond formation; Function experimentally demonstrated in the studied organism; enzyme.
 
  
 
0.987
dsbB
Disulfide bond formation protein B (Disulfide oxidoreductase); Required for disulfide bond formation in some periplasmic proteins. Acts by oxidizing the DsbA protein; Belongs to the DsbB family.
 
 
 0.943
rdoA
Conserved hypothetical protein, putative homoserine kinase type II; A protein kinase that phosphorylates Ser and Thr residues. Probably acts to suppress the effects of stress linked to accumulation of reactive oxygen species. Probably involved in the extracytoplasmic stress response.
 
    0.897
dipZ
Thiol:disulfide interchange protein DsbD; Required to facilitate the formation of correct disulfide bonds in some periplasmic proteins and for the assembly of the periplasmic c-type cytochromes. Acts by transferring electrons from cytoplasmic thioredoxin to the periplasm. This transfer involves a cascade of disulfide bond formation and reduction steps. Belongs to the thioredoxin family. DsbD subfamily.
 
 
 0.821
PSHAa0246
Homologs of previously reported genes of unknown function; carrier.
  
    0.799
dsbC
Disulfide bond isomerase, periplasmic; Required for disulfide bond formation in some periplasmic proteins. Acts by transferring its disulfide bond to other proteins and is reduced in the process; Belongs to the thioredoxin family. DsbC subfamily.
  
  
 0.690
trpCF
Bifunctional: indole-3-glycerolphosphate synthetase (N-terminal); Function of homologous gene experimentally demonstrated in an other organism; enzyme; Belongs to the TrpC family.
     
 0.684
PSHAa0245
Putative orphan protein; No homology to any previously reported sequences.
       0.607
PSHAa0244
Putative orphan protein; No homology to any previously reported sequences.
       0.606
bamE
Conserved protein of unknown function; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane.
  
  
 0.594
Your Current Organism:
Pseudoalteromonas haloplanktis
NCBI taxonomy Id: 326442
Other names: P. haloplanktis TAC125, Pseudoalteromonas haloplanktis TAC125, Pseudoalteromonas haloplanktis str. TAC125, Pseudoalteromonas haloplanktis strain TAC125
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